Senior Principal Scientist, Data Analytics and Pharmacometric Modeling

4 weeks ago


San Francisco, California, United States BioSpace, Inc. Full time
Job Details

At BioSpace, Inc., we are seeking a highly motivated Senior Principal Scientist to join our cross-functional global drug development teams in South San Francisco, CA.

The Clinical Pharmacology, Modeling & Simulation Department is responsible for developing and implementing novel data science and predictive analytics methodologies to support clinical drug development.

We are looking for a Subject Matter Expert who will apply innovative quantitative tools, such as AI/ML based analytics, multivariate statistical and empirical modeling, to complement the Pharmacokinetic/Pharmacodynamic (PK/PD) modeling approaches.

The ideal candidate will be responsible for developing and executing an integrated predictive analytics strategy to expand the role of pharmacometric analysis by incorporating novel data, including medical imaging and electronic health records.

Key responsibilities may include:

  • Design and implement AI/ML driven analytics to help with clinical drug development plans
  • Expand the pharmacometric modeling to include information from novel data sources
  • Adapt data science algorithms for modeling clinical trial data
  • Responsible for planning and implementation of analyses to integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics and disease states
  • Influence external environment through methods such as publication and presentations

We are seeking a leader with a Doctorate degree in Applied mathematics, Computer Science, Engineering or related field and 3 years of industry/academic experience, or equivalent qualifications.

Preferred qualifications include a PhD in Statistical and Data sciences, Computer Science, Pharmaceutical Sciences, Engineering, or related fields with equivalent professional degrees, and experience in developing methodologies and with knowledge of theoretical foundations of data science methods.

We offer a Total Rewards Plan comprising health and welfare plans, financial plans, work/life balance, and career development opportunities, including comprehensive employee benefits package, discretionary annual bonus program, stock-based long-term incentives, award-winning time-off plans, and flexible work models.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.



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