Lead Bioinformatics Specialist

2 weeks ago


Doral, Florida, United States University of Miami Full time
Position Overview:
The University of Miami is seeking a Lead Bioinformatics Specialist to join our dynamic team at the Sylvester Comprehensive Cancer Center. This role focuses on advancing our capabilities in quantitative proteomics through innovative methodologies and state-of-the-art techniques.

Key Responsibilities:
As a Lead Bioinformatics Specialist, your primary duties will include:
  • Engaging in mass-spectrometry based proteomics data generation, processing, and quality assurance analytics.
  • Managing and maintaining FASTA formatted databases for protein and peptide identification searches.
  • Processing RNA-seq data to align with mass spectrometry-derived protein and peptide mass and intensity data.
  • Conducting searches to translate m/z and intensity data into amino acid sequence information, culminating in protein-based results.
  • Performing statistical analyses on label-free quantitation, SILAC, and mass barcode (TMT) results to create visual representations such as volcano plots.

Qualifications:
  • A Bachelor's degree is required; a Master's or PhD in bioinformatics, applied mathematics, or large data analysis is preferred.
  • A minimum of 3 years of relevant experience in bioinformatics or a related field.
  • Proficiency in R-scripting and/or Perl scripting is essential.
  • Exceptional computer skills and familiarity with software tools such as MaxQuant, Sequest, Mascot, and Proteome Discoverer.
  • Strong written and verbal communication skills.
  • A collaborative spirit with a commitment to enhancing cancer diagnosis and care through proteomics.
  • A solid publication record is advantageous but not mandatory.

Benefits:
The University of Miami offers a competitive salary and a comprehensive benefits package, including medical, dental, and tuition remission.

About Us:
The University of Miami is dedicated to transforming lives through education, research, and service. As a vibrant academic and healthcare community, we strive for excellence and are committed to fostering a culture of belonging where every individual feels valued.
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