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Senior Robotics Engineer

2 months ago


Cambridge, Massachusetts, United States Beam Therapeutics Inc. Full time

Company Overview:
Beam Therapeutics is dedicated to creating a premier, fully integrated platform for precision genetic therapies.

To realize this goal, Beam has developed a comprehensive platform that encompasses a range of gene editing and delivery technologies while also establishing internal manufacturing capabilities.

At the core of Beam's gene editing technologies is base editing, a proprietary method designed to facilitate precise, predictable, and efficient single base modifications at targeted genomic sites, without inducing double-stranded breaks in the DNA.

This innovative approach has the potential to support a diverse array of therapeutic editing strategies, which Beam is leveraging to advance a varied portfolio of base editing initiatives.

Beam is a values-driven organization that prioritizes its workforce, cutting-edge scientific advancements, and a mission to provide enduring cures for patients afflicted by serious illnesses.


Responsibilities:
Engage in applied biochemistry within a team focused on developing innovative solutions for combating diseases and adverse medical conditions;

Enhance biochemistry research capabilities;

Advance laboratory automation systems;

Support in-vitro and in-vivo initiatives related to the development of next-generation base-editing technologies and novel drug delivery systems;

Refine biochemical delivery mechanisms;

Investigate discovery science;

Complete development projects and assignments in biochemistry;

Transform bench-top scientific processes into fully automated biotechnological workflows by validating liquid handlers and integrating automation systems;

Formulate actionable strategies to alleviate operational bottlenecks while boosting throughput and quality of biochemical data from existing processes;

Conduct biochemical testing with a focus on pharmaceutical candidates;

Generate documentation, troubleshoot, and provide support for automation-related challenges;

Facilitate knowledge transfer regarding methods developed for biochemistry and biotechnological applications;

Collaborate across functions to implement new technologies, protocols, and techniques aimed at creating state-of-the-art biotechnology solutions and enhancing internal automation infrastructure for discovery science and innovation in biochemistry and related fields;

Design and execute strategies that contribute to the development of novel therapeutic products in biochemistry and biotechnology; participate in technology transfer activities related to the therapy product portfolio; generate and optimize method protocols, including standard operating procedures;

Support process development and optimization; work with data, including its analysis, design, display, and visualization; analyze experimental results in biochemistry;

Report findings internally, sharing data and insights with Beam teams; document development and analysis;

Participate in internal team meetings and discussions, contributing to the generation of records used in these; document results and findings in a clear, scientifically accurate, and comprehensible manner;

Assist senior staff at Beam;

Stay updated on relevant literature in the field.

Qualifications:

One way to qualify:
Bachelor's degree or foreign equivalent in biochemistry, chemical engineering, biochemical engineering, pharmaceutical sciences, biotechnology, or a related discipline, plus:

Experience in laboratory automation;

Proficiency with liquid handlers;

Familiarity with specific laboratory automation equipment from Hamilton Vantage, Labcyte/Beckman Echo, HighRes Biosolutions, Precise Robotics, and Tecan Fluent;

Experience in high-throughput sample preparation and processing;

Knowledge of next-generation sequencing;

Experience with laboratory information management systems, specifically Benchling;

5 years of progressive, post-baccalaureate experience in all of the following areas, demonstrated through appropriate graduate-level coursework, research, or lab work:

Other way to qualify:
Alternatively, may qualify with a Master's Degree or foreign equivalent in biochemistry, chemical engineering, biochemical engineering, pharmaceutical sciences, biotechnology, or a related field, plus:

Experience in laboratory automation;

Proficiency with liquid handlers;

Familiarity with specific laboratory automation equipment from Hamilton Vantage, Labcyte/Beckman Echo, HighRes Biosolutions, Precise Robotics, and Tecan Fluent;

Experience in high-throughput sample preparation and processing;

Knowledge of next-generation sequencing;

Experience with laboratory information management systems, specifically Benchling;

2 years of experience in all of the following areas, demonstrated through appropriate graduate-level coursework, research, or lab work:

Other Information:
This is a permanent, full-time position that is immediately available;

The role is primarily laboratory-based and does not require travel;

Telecommuting is not permitted due to the laboratory-based nature of the work;

Candidates must reside within a reasonable commuting distance to the workplace;

This position does not involve supervisory responsibilities over other personnel and is intended for a hands-on individual contributor.