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Scientist, T Cell Engineer
2 months ago
Job Title: Scientist, T Cell Engineering
Job Summary:
We are seeking a highly skilled Scientist, T Cell Engineering to join our team at OverT Bio. As a key member of our research team, you will be responsible for developing and refining viral and non-viral engineering strategies for modification of primary human T cells. Your expertise in T cell engineering, in vitro and in vivo characterization, and research-scale manufacturing process development will be crucial in advancing our cutting-edge technologies.
Key Responsibilities:
- Develop and design viral and non-viral engineering strategies for modification of primary human T cells.
- Design, execute, and analyze complex experiments across both in vitro and in vivo systems for characterization of engineered T cells in the context of solid tumor cancers.
- Utilize cutting-edge high throughput and multi-omic technologies to discover biomarkers of optimal human donors for an effective engineered T cell product.
- Become a subject matter expert able to find creative solutions to unexpected problems.
Requirements:
- PhD in Immunology or equivalent.
- Minimum of 2 years of cell therapy experience in industry.
- Experience with primary human T cell engineering is essential.
- Experience with gamma delta T cells or TCR-transduced T cells is preferred.
- Demonstrated proficiency with viral vector design and generation.
- Demonstrated proficiency with flow cytometry, co-culture assays, cytotoxicity, and other immune-related assays.
- Willingness to quickly discover and learn new methods and approaches.
- Ability to adjust rapidly to shifting priorities and deliver high-quality, detail-oriented results in a timely manner.
- Teamwork and collaborative attitude are essential.
- Strong organizational and record-keeping skills.
- Authorized to work in the US.
What We Offer:
- Competitive compensation commensurate with experience.
- Employee stock options.
- Medical, dental, and vision benefits (100% premium covered by the employer).
- 401(k) with 100% match on first 5% of employee contributions.
- 15 days vacation, with one day added after every year of service.
- 10 paid federal and other major holidays.
