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Director of Data Science

2 months ago


Seattle, Washington, United States A-Alpha Bio Full time
Job Overview

A-Alpha Bio is a biotechnology company that leverages cutting-edge technologies to measure, predict, and engineer protein-protein interactions. We are seeking a seasoned Director of Data Science to lead a team of skilled data scientists in driving our in-house drug discovery pipeline and collaborating with major biopharma partners.

Key Responsibilities
  • Grow and manage a high-performing team of data scientists working on computational analysis of various internal and external projects.
  • Represent A-Alpha Bio to external stakeholders by leading data science efforts for major partnerships.
  • Independently identify and pursue methodological improvements and new scientific objectives within areas of expertise.
  • Work closely with colleagues to maximize the impact of computational analysis for ongoing drug discovery and optimization campaigns.
  • Participate in the publication of research papers and filing of patents.
  • Perform other duties as assigned.
Requirements
  • PhD in a related field with 10+ years of experience and 5+ years of management experience; or an equivalent combination of education and experience.
  • Direct experience in statistical treatment of high-throughput biological data, as well as in the application of deep learning to high-throughput biological sequence data.
  • Familiarity with state-of-the-art machine learning techniques in at least one of the following areas: antibody or protein engineering, drug discovery, NGS-based assays, and/or synthetic biology.
  • Proven leadership in recruiting and managing high-performing teams of scientists and engineers in a cross-functional and fast-paced environment, with a history of maximizing and growing internal talent.
  • Ability and desire to contribute to applied data science as an expert individual contributor in addition to management duties.
  • Impressive technical track record at leading pharma/biotech companies.
  • Strong interpersonal, verbal/written communication, and problem-solving skills.
Preferred Qualifications
  • Experience with contracting, business development, and alliance management in the context of pharma/biotech partnerships.
  • Experience with the application of natural language processing techniques to high-throughput biological sequence data at scale.
  • Experience creating and maintaining deployment pipelines with CI/CD tools.
  • Expertise with Python, Pandas, Pytorch, and Amazon Web Services.
About A-Alpha Bio

A-Alpha Bio is a biotechnology company that leverages synthetic biology and machine learning to measure, predict, and engineer protein-protein interactions. Our AlphaSeq platform applies synthetic biology to experimentally measure millions of protein interaction affinities simultaneously. Protein binding data is incorporated into our AlphaBind platform to train machine learning models that predict binding from sequence. We use both platforms to discover and optimize high-impact therapeutics for our pipeline and in partnership with leading pharmaceutical and biotechnology companies.

We are building a diverse, meritocratic, and supportive team that shares our values of speaking the truth, shooting for the moon, taking the reins, playing for the team, and improving the world. We are headquartered in a custom designed lab and office space in downtown Seattle's Belltown neighborhood. While the startup lifestyle occasionally requires grueling hours, we strongly value the need for a work-life balance. We are fortunate to be situated in a region that is renowned for its premier outdoor activities, including hiking, biking, climbing, skiing, kayaking, sailing, and more.