Senior Principal Scientist

4 days ago

Princeton, New Jersey, United States Bristol-Myers Squibb Company Full time
Job Summary

Bristol-Myers Squibb Company is seeking a highly skilled Senior Principal Scientist to join our Translational Medicine team in Neurology. As a key member of our late-stage team, you will be responsible for leading translational and clinical biomarker activities to support drug development programs in multiple diseases in neurology and neuropsychiatry.

Key Responsibilities
  • Design and implement program-specific biomarker/translational plans, responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.
  • Determine appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable.
  • Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs;
  • Prepares and delivers internal and external translational/biomarker presentations.
  • Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed.
  • Keeps up-to-date on relevant scientific/technical literature in order to applying external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biology.
  • Works with TM laboratory scientists and academic TLs to address nonclinical translational questions.
  • Participates in post-hoc biomarker analysis and publication efforts.
  • Supports regulatory submissions and regulatory interactions as needed.
Requirements
  • Understanding of late stage drug development.
  • Experience in activities required for and related to clinical trial initiation, maintenance and completion.
  • Experience in interacting with CROs and TLs to manage projects and timelines.
  • Proven scientific/leadership expertise (working in teams, mentoring people, managing projects).
  • Accountable for timelines and deliverables.
  • Prioritizes risks and implements contingency plans.
  • Communicates regularly; prepares and delivers presentations within the department, to governance and senior leadership bodies, and externally as requested.
  • Recognizes cross-functional issues and communicates within the larger organization.
  • Provides expert guidance to multi-disciplinary teams and senior management.
  • Has a track record of delivering results, driving continuous improvements, and building effective cross-functional networks.
  • Ability to prioritize and manage time efficiently.
  • Strong verbal and written communication skills.
  • Accurate and detailed record keeping.
  • Excellent organizational skills.
Education and Experience
  • Bachelor's Degree.
  • 10+ years of academic and/or industry experience.
  • Or Master's Degree.
  • 8+ years of academic and/or industry experience.
  • Or Ph.D. or equivalent advanced degree in the Life Sciences.
  • 6+ years of academic and/or industry experience.
  • 2+ years of leadership experience.
Preferred Qualifications
  • Ph.D. in neuroscience or related field.
  • 8+ years of academic/biotech experience.
  • Minimum 3 years of clinical biomarker experience.

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