Senior Scientist, Immune Cell Biology Specialist

5 days ago

Cambridge, Massachusetts, United States Flagship Ventures Full time
Company Overview

FL87, Inc. is a pioneering biotechnology company at the forefront of gene therapy innovation. Founded by Flagship Pioneering, a renowned innovation enterprise, FL87 is dedicated to developing novel approaches to address currently untreatable diseases.

Job Summary

We are seeking an experienced and enthusiastic Senior/Principal Scientist to lead efforts in characterizing nucleic acid function, localization, and responses in immune cells. This individual will have the opportunity to work in a dynamic and fast-paced entrepreneurial environment as part of a highly collaborative team.

Key Responsibilities
  • Design, execute, and troubleshoot functional T cell assays
  • Utilize a deep understanding of immune cell biology to screen nucleic acid function at both the cellular and molecular level
  • Employ a deep understanding of CAR function and immune cell fitness to advance cell therapy projects in vitro and in vivo
  • Proficient at analysis of nucleic acid function (Flow-cytometry, Incucyte, microscopy, qPCR, HiBit/luciferase, Cre/lox, etc)
  • Track record of solid managerial experience and scientific leadership
  • Effectively communicate experimental methods and findings in both oral and written formats
  • Maintain a workload of multiple concurrent projects and rapidly adjust experimental priorities to align with company priorities
  • Comfortable working both independently and collaboratively in a multidisciplinary team environment
Qualifications
  • Ph.D. in Biology, Immunology, Virology, or related field with 3-6 years of industry experience
  • Broad experience in cellular biology, immunology, and virology, particularly as relevant for the functionalization of nucleic acids in the context of immune cells
  • Experience with CAR-T design and assay development is a bonus: cancer cell killing, receptor density characterization, etc
  • Enthusiasm for working at the bench
  • Strong communication and interpersonal skills
  • Strong organizational, analytical, and problem-solving skills
  • Interest in developing new skills
  • Ability to thrive in a fast-paced, multidisciplinary, and rapidly growing biotech environment
About Flagship Pioneering

We are a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value.

We believe pioneering is best done by teams, and that it is a process that can be taught, learned, and replicated. Learn more about our Company Creation Model.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status.

We recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

  • Research Scientist II

    3 weeks ago

    Cambridge, Massachusetts, United States Repertoire Immune Medicines Full time

    Job Title: Research Associate II/Senior Research AssociateJob SummaryRepertoire Immune Medicines is seeking a highly motivated Research Associate II/Senior Research Associate to join the Applied Immunology team. This team is responsible for innovation and early development of Repertoire's immunotherapeutics. The successful candidate will support a team of...

  • Senior/Principal Scientist, Biology

    2 weeks ago

    Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full time

    About the OpportunityCrossbow Therapeutics, Inc. is a biotechnology company dedicated to improving the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. Our T-BoltTM therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell...

  • Data Scientist, Computational Biology

    3 weeks ago

    Cambridge, Massachusetts, United States Repertoire Immune Medicines Full time

    Job DescriptionRepertoire Immune Medicines is a biotechnology company dedicated to unlocking the potential of the human immune system to treat cancer and autoimmune diseases. Our team is working to develop novel targeted immune medicines using the DECODE platform, which enables in-depth characterization of TCR-antigen pairs. We are seeking a talented Data...

  • Research Scientist

    4 weeks ago

    Cambridge, Massachusetts, United States GC Therapeutics Full time

    Job Title: Research Associate - Stem Cell BiologyGC Therapeutics is a pioneering genome-wide cell landscape exploration company that leverages an integrated synthetic biology and AI-driven platform for cell programming. Our patent-pending and proprietary pluripotent stem cell differentiation technology platform, TFomeTM, was developed in Professor George...

  • Research Scientist, Stem Cell Biology

    3 weeks ago

    Cambridge, Massachusetts, United States GC Therapeutics Full time

    Job Title: Research Associate, Stem Cell BiologyGC Therapeutics is a pioneering genome-wide cell landscape exploration company that leverages an integrated synthetic biology and AI-driven platform for cell programming. Our patent-pending and proprietary pluripotent stem cell differentiation technology platform, TFomeTM, was developed in Professor George...

  • Computational Biology Research Scientist

    4 weeks ago

    Cambridge, Massachusetts, United States PSG Global Solutions Full time

    Job Title: Computational Biology Associate ScientistWe are seeking a highly skilled Computational Biology Associate Scientist to join our team at PSG Global Solutions in Cambridge. As a key member of our Biotechnology/Medical Devices team, you will play a crucial role in advancing our research and development programs.Responsibilities:Generate high-quality...

  • Scientist Cellular Genomics Specialist

    4 weeks ago

    Cambridge, Massachusetts, United States Net2Source Inc. Full time

    Job Title: ScientistPlease find below the job description:Job Summary:We are seeking a highly skilled Scientist to join our Systems Immunology Lab in our Inflammation & Immunology Research Unit. The successful candidate will be responsible for generating and processing single-cell, spatial, and functional genomics data, as well as supporting standard...

  • Senior Research Scientist

    4 weeks ago

    Cambridge, Massachusetts, United States SIMCERE OF AMERICA, INC Full time

    Simcere of America, Inc. is expanding its Boston Innovation Center with a dynamic drug discovery team based in Cambridge, Massachusetts. We are seeking a highly skilled and innovative Associate Scientist to enhance our preclinical research division.Key Responsibilities:Design and execute cell-based assays to identify potential targets, utilizing a range of...

  • Senior Scientist, Cell-based Assays Specialist

    1 day ago

    Cambridge, Massachusetts, United States Fable Therapeutics Full time

    About UsFable Therapeutics is a pioneering biotechnology company that leverages cutting-edge structure and sequence-based protein language models to drive therapeutic innovation. Founded by visionary leaders in machine learning and biotech, we have established a strong foundation for our internal therapeutic pipeline and are collaborating with top pharma...

  • Senior Director, Biology

    3 weeks ago

    Cambridge, Massachusetts, United States Fog pharma Full time

    Transformative Drug Modality OpportunityFogPharma is pioneering the discovery and development of Helicon therapeutics, peptides capable of efficient cell entry and modulation of both protein-protein and protein-DNA interactions. As a Senior Director, Biology, you will lead one of our cross-functional teams responsible for timely progression of a novel...

  • Scientist

    4 weeks ago

    Cambridge, Massachusetts, United States Net2Source Inc. Full time

    Job Title: ScientistLocation: Cambridge, MADuration: 06+ Month ContractPayrate: $35- $39/hr on w2 without benefitsKey Responsibilities:We are seeking a skilled scientist to join our Systems Immunology Lab in Net2Source Inc.'s Inflammation & Immunology Research Unit. The successful candidate will be responsible for generating and processing single-cell,...

  • Research Scientist

    4 days ago

    Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full time

    Research Scientist 2Biological Engineering-Synthetic Biology Center-Weiss LabWe are seeking a highly skilled Research Scientist to join our interdisciplinary research lab. The successful candidate will contribute to the development of integrated biological systems capable of autonomously performing tasks related to therapeutic agents for various...

  • Research Associate Stem Cell Biology

    2 weeks ago

    Cambridge, Massachusetts, United States GC Therapeutics Full time

    About GC TherapeuticsGC Therapeutics is a pioneering genome-wide cell landscape exploration company that leverages an integrated synthetic biology and AI-driven platform for cell programming. Its proprietary pluripotent stem cell differentiation technology platform TFomeTM was developed in Professor George Church's lab, a renowned expert in synthetic...

  • Senior Scientist, Disease Area Biology

    2 weeks ago

    Cambridge, Massachusetts, United States Korro Bio, Inc. Full time

    Job Summary:Korro Bio, Inc. is seeking a highly motivated and experienced Senior Scientist to join our Disease Area Biology team. As a key member of our team, you will contribute to and lead drug discovery efforts for brain and spinal cord disorders. The successful candidate will design and conduct experiments in human cell lines to advance discovery...

  • Research Scientist Cell Pharmacology

    7 days ago

    Cambridge, Massachusetts, United States Novartis Group Companies Full time

    Job Title: Research Scientist, Cell PharmacologyWe are seeking a highly motivated Research Scientist to join our Cell Pharmacology team at Novartis Group Companies.About the Role:This is an exciting opportunity to advance our understanding of disease biology, contribute to target identification efforts, and work towards the discovery and optimization of new...

  • Associate Scientist in In Vivo Biology

    2 months ago

    Cambridge, Massachusetts, United States GC Therapeutics Full time

    In Vivo Research ScientistCompany OverviewGC Therapeutics is pioneering the exploration of genome-wide cell landscapes through an innovative synthetic biology and AI-driven platform for cell programming. Our proprietary pluripotent stem cell differentiation technology, TFomeTM, was developed in collaboration with Professor George Church's lab, a leader in...

  • Senior Scientist, Process Development Expert

    3 weeks ago

    Cambridge, Massachusetts, United States Kytopen Full time

    Job Title: Senior Scientist, Process DevelopmentWe are seeking a highly skilled Senior Scientist, Process Development to join our team at Kytopen. As a key member of our scientific research team, you will be responsible for planning and executing scientific efforts to support the development of our Flowfect technology platform.Responsibilities:Design and...

  • Bioinformatics Specialist

    4 weeks ago

    Cambridge, Massachusetts, United States eTeam Full time

    Job Title: Bioinformatics SpecialistLocation: Cambridge, MADuration: 6 monthsPay Rate: $40/hrJob Description:We are seeking a skilled scientist to join our Systems Immunology Lab in eTeam's Inflammation & Immunology Research Unit. The successful candidate will be responsible for generating and processing single-cell, spatial, and functional genomics data, as...

  • Research Scientist, In Vivo Biology

    4 weeks ago

    Cambridge, Massachusetts, United States GC Therapeutics Full time

    Job Title: Research Associate, In Vivo BiologyAbout the Role:GC Therapeutics is seeking a highly skilled and detail-oriented Research Associate to join our preclinical team. As a key member of our team, you will support the execution of in vivo studies, including rodent models, and contribute to the development of cell therapies.Key Responsibilities:Design,...

  • Research Scientist, In Vivo Biology

    2 weeks ago

    Cambridge, Massachusetts, United States GC Therapeutics Full time

    Job Title: Research Associate, In Vivo BiologyGC Therapeutics is seeking a highly skilled and detail-oriented Research Associate to join our growing preclinical team. As a key member of our team, you will support the execution of in vivo studies, including rodent models, and contribute to the development of unique cell therapies.Key Responsibilities:Design,...