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Senior Scientist, Process Development Expert
2 months ago
We are seeking a highly skilled Senior Scientist, Process Development to join our team at Kytopen. As a key member of our scientific research team, you will be responsible for planning and executing scientific efforts to support the development of our Flowfect technology platform.
Responsibilities:- Design and conduct experiments to develop and support Kytopen's Flowfect technology, product development, and characterization.
- Lead scientific efforts with both internal strategic development and customer-driven projects to ensure milestones are delivered with targets achieved.
- Collaborate with the Engineering team to define requirements, specifications, and procedures for Flowfect technology platforms.
- Work with external collaborators to define project workplans, align on deliverables and milestones, and technology transfer.
- Serve as a subject matter expert in internal and external scientific efforts utilizing the Flowfect technology.
- Perform in vitro cellular assays with an emphasis on flow cytometry and PCR.
- Ensure excellent laboratory approach, adherence to protocol, and meticulous lab documentation.
- Generate high-quality experimental reports for internal and external presentation and review.
- Perform statistical analysis on characterization/validation data.
- Maintain shared responsibility of inventory management, equipment maintenance, and continuous process improvement.
- Advanced degree (M.S. or Ph.D.) in biological engineering, chemical engineering, immunology, or a related field.
- At least 6 years of industry experience with a biotech, diagnostic, pharmaceutical company (at least 3 years with a Ph.D.).
- Experience working with human HSC and/or immune cell biology, including ex vivo culture and genetic manipulation of primary cell types, and viral and non-viral biomolecule delivery.
- Experience developing control strategies (PAR and NOR), conducting risk assessments (FMEA), and creating scale-down models.
- Experience in standard processing techniques including multi-parameter flow cytometry, molecular biology, immunological assays, and cell culture.
- Familiarity with gene editing via current technologies (e.g. CRISPR, TALENs), including the ability to perform CRISPR screens with downstream functional assays.
- Experience with leveraging high-throughput screening for drug discovery and development.
- Experience with design of experiments tools such as JMP and practical knowledge of statistical analysis.
- Strong organizational, analytical, problem-solving, root-cause-analysis, and trouble-shooting skills.
- Strong written and verbal communication skills.
We are a values-driven, creative team, and we know that we're only successful because of the talented people on our team. We offer competitive compensation, including a 401k match and equity, a comprehensive package of health benefits, and a supportive work environment that includes hybrid work schedules, flexible vacation, paid family leave, and continuing education support.
We are committed to building a diverse and inclusive workplace, and we encourage applications from candidates who are passionate about our mission and values.
