Computational Immunology Leader

4 days ago


Chicago, Illinois, United States Tempus AI Inc. Full time
Job Title: Computational Immunology Leader

Estimated Salary: $180,000 - $250,000 per year

At Tempus AI Inc., we are seeking a highly skilled Computational Immunology Leader to join our team. This role involves leading and overseeing projects leveraging our proprietary platform to support biopharmaceutical partners in advancing their drug discovery portfolio, with a focus on immuno-oncology.

The ideal candidate will possess immunology training, experience in TCR/BCR immune repertoire sequencing, genomic and clinical data analytical skills, a positive and dynamic leadership style, and the ability to communicate complex scientific findings to various stakeholders.

Key Responsibilities:

  • Team Management:
    • Lead a dynamic team of computational scientists executing translational or real-world evidence projects integrating molecular and clinical data from our multimodal data platform to derive insights for biopharma partners.
    • Establish best practices for reproducibility, help identify analytical gaps, and suggest next steps.
  • Scientific Execution:
    • Design, develop, and execute computational immunology research projects of high complexity.
    • Support exploratory research for target discovery and validation in pre-clinical and early phases of drug development.
    • Support decisions for early-stage assets such as patient and indication selection, biomarker, and combination strategies.
    • Evaluate clinical trial design by testing assumptions, refining eligibility criteria, and characterizing patient outcomes on standard of care.
  • Stakeholder Collaboration:
    • Work closely with internal teams, including key account directors, business development, operations, alliance management, and research informatics, to align team initiatives with broader business goals.
    • Support the development of specific account strategies in coordination with the account team to expand accounts into strategic collaborations.
  • Reporting & Presentation:
    • Oversee the generation of contracted deliverables and executive summaries for biopharma customers.
    • Collaborate with external partners to establish Tempus as a trusted advisor to expand research partnerships.
  • Project Management:
    • Work closely with the alliance manager for the execution, and deliverables of research projects, ensuring that they are completed on time, within budget, and in accordance with contracted specifications.
  • Continuous Improvement:
    • Stay current with industry trends, best practices, and advancements in computational oncology research.
    • Apply this knowledge to enhance research methodologies and improve overall research quality on the team.
    • Become an expert in our biopharma partners' strategy, pipeline, and portfolio to proactively determine all areas in the Tempus platform that could add value to the drug development process of our partners.
    • Work with Product and Engineering teams to streamline the workflow of computational analyses.
    • Build relationships with R&D and commercial executives internally and at partner organizations, enabling identification, development of, and support for additional value-creation opportunities.


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