Scientific Researcher

7 days ago


Chicago, Illinois, United States The Chan Zuckerberg Biohub, Inc. Full time
About the Role

As a Postdoctoral Fellow at The Chan Zuckerberg Biohub, you will have the opportunity to contribute to cutting-edge research in the field of T cell immunology. Our team is dedicated to understanding the mechanisms and design principles of TCR and immune epitopes.

Job Description

We are seeking an outstanding early-career scientist or engineer to join our collaborative project aimed at understanding the presentation, binding, and activation principles of TCR and related immune epitopes. This position offers a unique opportunity to work on a highly interdisciplinary project, leveraging expertise from computational biologists and bioinformaticians to integrate AI and ML technologies.

Key Responsibilities
  • Conduct wet-lab experiments to explore the presentation, binding, and activation principles of TCR and related immune epitopes
  • Develop novel protein-protein interaction (PPI) models to predict the behavior of specific TCRs against various immune epitopes
  • Utilize PPI models to design TCRs for immune cell-based therapies targeting different inflammatory diseases
  • Collaborate with computational biologists and bioinformaticians to integrate AI and ML technologies
  • Supervise junior trainees, maintain detailed documentation of experiments and procedures, and engage in scientific communication
Requirements
  • PhD in Immunology, Bioengineering, Bioinformatics, or a related field
  • At least 2 years of work experience in T cell immunology
  • High motivation to advance scientific training and contribute to the collaborative research environment at CZ Biohub
  • Active participation in team efforts to decode TCR design principles
  • Effective collaboration and engagement with colleagues across the Biohub to uphold our values of excellence, innovation, and partnership
What We Offer
  • Resources to disrupt and innovate at the frontiers of our knowledge of biology and disease
  • A collegial and collaborative environment consisting of diverse expertise
  • Access to collaborators, resources and facilities at our three partner universities and at partner organizations in Chicagoland and beyond
  • Competitive compensation: $80,000 - $110,000 per year, commensurate with experience
Benefits
  • Healthcare coverage
  • Life and disability insurance
  • Commuter subsidies
  • Fertility care
  • Childcare stipend
  • 401(k) match
  • Flexible time off
  • Generous parental leave policy
About Us

The Chan Zuckerberg Biohub is an independent nonprofit research institute that brings together three powerhouse universities into a single collaborative technology and discovery engine. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.


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