Scientific Researcher
7 days ago
As a Postdoctoral Fellow at The Chan Zuckerberg Biohub, you will have the opportunity to contribute to cutting-edge research in the field of T cell immunology. Our team is dedicated to understanding the mechanisms and design principles of TCR and immune epitopes.
Job DescriptionWe are seeking an outstanding early-career scientist or engineer to join our collaborative project aimed at understanding the presentation, binding, and activation principles of TCR and related immune epitopes. This position offers a unique opportunity to work on a highly interdisciplinary project, leveraging expertise from computational biologists and bioinformaticians to integrate AI and ML technologies.
Key Responsibilities- Conduct wet-lab experiments to explore the presentation, binding, and activation principles of TCR and related immune epitopes
- Develop novel protein-protein interaction (PPI) models to predict the behavior of specific TCRs against various immune epitopes
- Utilize PPI models to design TCRs for immune cell-based therapies targeting different inflammatory diseases
- Collaborate with computational biologists and bioinformaticians to integrate AI and ML technologies
- Supervise junior trainees, maintain detailed documentation of experiments and procedures, and engage in scientific communication
- PhD in Immunology, Bioengineering, Bioinformatics, or a related field
- At least 2 years of work experience in T cell immunology
- High motivation to advance scientific training and contribute to the collaborative research environment at CZ Biohub
- Active participation in team efforts to decode TCR design principles
- Effective collaboration and engagement with colleagues across the Biohub to uphold our values of excellence, innovation, and partnership
- Resources to disrupt and innovate at the frontiers of our knowledge of biology and disease
- A collegial and collaborative environment consisting of diverse expertise
- Access to collaborators, resources and facilities at our three partner universities and at partner organizations in Chicagoland and beyond
- Competitive compensation: $80,000 - $110,000 per year, commensurate with experience
- Healthcare coverage
- Life and disability insurance
- Commuter subsidies
- Fertility care
- Childcare stipend
- 401(k) match
- Flexible time off
- Generous parental leave policy
The Chan Zuckerberg Biohub is an independent nonprofit research institute that brings together three powerhouse universities into a single collaborative technology and discovery engine. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.
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