Principal Scientist Bioprocess Development Lead

14 hours ago


Gaithersburg, Maryland, United States Cartesian Therapeutics Full time
Job Opportunity

We are seeking a highly skilled Principal Scientist to join our team at Cartesian Therapeutics. As a key member of our bioprocess development team, you will be responsible for designing, developing, and executing experiments for bioprocess development, optimization, and characterization of CAR-T cell therapy.

Key Responsibilities:

  • Develop and execute bioprocess development strategies to support Phase I & II enabling activities.
  • Collaborate with internal and external partners to manage sample testing and critical raw material manufacturing.
  • Provide technical oversight and support for IND filling and clinical manufacturing.
  • Support initiatives for new technology development and continuous improvement projects.
  • Author technical reports and protocols to enable technology transfer and manufacturing activities.

Requirements:

  • PhD in Chemical Engineering, Biochemistry, Cell Biology, or related field with at least 7 years of relevant industry experience.
  • Experience with mammalian cell culture bioreactor technologies, including perfusion.
  • Excellent communication and team leadership skills.

Preferred Qualifications:

  • Working knowledge of statistics and Design of Engineering (DoE) approach.
  • Experience with T-cells or other immune cell selection, expansion, and culture.
  • Experience with flow cytometry and ELISA assays.

Cartesian Therapeutics is an Equal Opportunity Employer and is committed to fostering an inclusive environment. We offer a competitive salary range of $140,000 to $165,000 per year, based on experience and qualifications. We believe in rewarding our team members fairly and encourage open discussions about compensation throughout the hiring process.



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