Senior Scientist Upstream Cell Culture Process Development

20 hours ago


Gaithersburg, Maryland, United States Salubris Biotherapeutics Inc Full time
Job Overview

Salubris Biotherapeutics, Inc. is seeking a highly skilled and experienced Scientist III/Principal Scientist to lead our Upstream Cell Culture Process Development Team. As a key member of our team, you will be responsible for driving the development and optimization of upstream cell culture processes for our antibody-based pipeline programs.

Key Responsibilities
  • Develop and implement cell line development strategies to ensure optimal cell line productivity and product quality.
  • Lead process development and optimization activities, including scale-up and technology transfer, to support clinical and commercial manufacturing.
  • Design and execute experiments using design of experiments (DOE) methodologies to optimize cell culture processes.
  • Characterize and validate upstream cell culture processes to ensure compliance with regulatory guidelines and quality standards.
  • Collaborate with cross-functional teams to ensure seamless technology transfer from lab-scale to commercial production.
  • Provide technical leadership and guidance on cell culture process development strategies and medium optimization.
  • Drive innovation and continuous improvement initiatives to enhance cell line development and upstream cell culture processes.
Requirements
  • Master's degree or Ph.D. in Chemical Engineering, Biochemical Engineering, or related field.
  • 10-12 years of hands-on experience in upstream cell culture process development, scale-up, and technology transfer within the biopharmaceutical industry.
  • Strong understanding of design of experiments (DOE) methodologies and their application in process optimization.
  • Demonstrated experience in later-stage cell culture process characterization and commercialization readiness.
  • Cell line development and characterization of Master and Working Cell Bank management experience highly preferred.
  • 2+ years of managerial experience leading team of scientist(s) and/or associates.
What We Offer
  • Competitive salary and bonus structure.
  • 401(k) matching and comprehensive benefits package.
  • Opportunities for professional growth and development.
  • Collaborative and dynamic work environment.


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