Assay Development Scientist

4 weeks ago


Gaithersburg, Maryland, United States Kelly Science, Engineering, Technology & Telecom Full time
Assay Development Scientist (Viral Neutralization/Automation)

Kelly Government Solutions is a trusted partner to the federal government and its key suppliers, offering a unique opportunity to work with the National Institutes of Health (NIH) in Gaithersburg, MD.

This is a full-time, long-term contract position that offers:

  • Competitive salary with comprehensive benefits package
  • Opportunity to work at NIH, the world's foremost medical research center
  • Learn more about what Kelly can do for you at our website

Job Summary:

The NIH is seeking an experienced Assay Development Scientist (Viral Neutralization/Automation) to join our laboratory team, specializing in viral neutralization assays, cell culture, viral transfection, and immunological evaluations, specifically utilizing automated systems such as the Biomek system.

Key Responsibilities:

  • Develop and optimize various neutralization assays
  • Maintain specimen samples and ensure laboratory compliance with Good Clinical Laboratory Practice (GCLP) guidelines
  • Perform rigorous data analysis using statistical methods to identify correlations and trends
  • Conduct reverse genetic rescues and pseudotype virus transfection propagations for large-scale assays
  • Evaluate human and animal samples in clinical trials through immunological methods
  • Analyze trial data using statistical methods to identify patterns and generate summary graphs
  • Prepare and qualify laboratory reagents, documenting processes accurately
  • Safely handle and process sera and other biological samples for assays
  • Perform precise liquid handling using serological, single, and multichannel pipettes, as well as automated liquid handling systems
  • Optimize and execute various neutralization assays on multiple platforms, including automated systems like Biomek i7 and Integra AssistPlus
  • Train analysts in assay protocols, especially those required in a GCLP environment
  • Schedule and conduct preventative maintenance on laboratory equipment following GCLP requirements
  • Follow SOPs to test samples in an organized, aseptic, high-throughput manner
  • Maintain rapid turnaround times for specimen samples while upholding accuracy standards
  • Manage supplies and reagents for scheduled tests and adapt to changes in schedule as needed
  • Comply with GCLP guidelines and maintain accurate records
  • Wear appropriate PPE in a BSL-2 laboratory and properly utilize various laboratory equipment
  • Store clinical samples using dry ice, freezers, and liquid nitrogen tanks, following safety protocols
  • Communicate effectively with management and external collaborators

Requirements:

  • Bachelor's degree (BS) with a minimum of 3 years of experience in a BSL-2 laboratory. PhD and additional industry experience strongly preferred.
  • Strong experience with viral neutralization assays.
  • Strong experience in a GCLP environment and expertise with Beckman Coulter automated liquid handling software like SAMI and Biomek.
  • Experience with cell culture and viral transfections.
  • Proficient in computer and data management programs such as LIMS, CQMS, and Microsoft Office.
  • Ability to work both collaboratively and independently.
  • Proficient in CQMS, LabKey, and Prism GraphPad software.


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