Principal Scientist Bioprocess Development Lead

1 month ago


Gaithersburg, Maryland, United States Cartesian Therapeutics Full time
Join Our Team as a Principal Scientist Bioprocess Development

At Cartesian Therapeutics, we are redefining the boundaries of Cell Therapies with groundbreaking innovations to address autoimmune diseases. We are seeking a highly skilled Principal Scientist to spearhead process development/optimization and GMP manufacturing support for Phase I & II enabling activities.

Responsibilities:
  • Design, develop, and execute experiments for bioprocess development, optimization, and characterization of CAR-T cell therapy.
  • Collaborate with internal and external partners to manage sample testing, critical raw material manufacturing, and ensure seamless technology transfer.
  • Provide technical oversight to support IND filling and ensure successful clinical manufacturing execution.
  • Support initiatives for new technology development and continuous improvement projects.
  • Author technical reports, protocols, SOPs, and risk assessments to facilitate technology transfer, manufacturing, and IND activities.
Qualifications:
  • PhD in Chemical Engineering, Biochemistry, Cell Biology, or a related field with at least 7 years of relevant industry experience.
  • Experience with various mammalian cell culture bioreactor technologies, including perfusion (Upstream process).
  • Excellent team player with strong communication skills and indirect/direct leadership experience in a multi-functional team setting.
Preferred Qualifications:
  • Working knowledge of statistics and experience with Design of Engineering (DoE) approach.
  • Experience with T-cells or other immune cell selection, expansion, and culture.
  • Experience with flow cytometry and ELISA assays.

We are committed to transparency and equity in our compensation practices. The salary range for this position is $140,000 to $165,000 per year, with the final salary determined based on factors such as years of experience, industry experience, education, and specific skills relevant to the role.

Cartesian Therapeutics is an Equal Opportunity Employer and is dedicated to fostering an inclusive environment where all employees are treated fairly without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, ancestry, disability, marital status, genetic information, military status, or any other characteristic protected under applicable law.



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