Lead, Viral Vector Stable Cell Line Development Expert
5 days ago
Takeda Pharmaceutical is a patient-focused company that transforms patient care through the development of novel specialty pharmaceuticals and best in class patient support programs.
Job DescriptionWe are seeking a highly experienced Viral Vector Stable Cell Line Development Expert to join our team. As a key member of our Cell Therapy pipeline, you will be responsible for overseeing all aspects of viral vector stable cell line development, including cloning, screening, characterization, stability, and productivity evaluation.
You will work closely with cross-functional teams to establish GMP-ready stable Viral Vector producer cell lines, from concept initiation to delivering top-performing clones. Your expertise will be instrumental in managing collaborations across CMC, Strategy, and Research teams to ensure timely delivery of robust stable producer clones.
Key Responsibilities:- Lead all aspects of viral vector stable cell line development, including cloning, screening, characterization, stability, and productivity evaluation.
- Partner with the Viral vector strategy team to develop and execute strategies for generating stable Viral vector producer cell lines for Gamma Retrovirus.
- Collaborate with Upstream & Downstream Viral Vector Process development teams to design, develop, and optimize robust viral production processes.
- Apply genomics, transcriptomics, and analytical assays such as Viral Vector titration assay, DNA sequencing, PCR, Southern/Northern blots, to comprehensive cell line characterization and optimization.
- Ensure compliance with regulatory requirements and industry standards for stable cell line development and viral vector production.
- PhD degree in Virology, Molecular biology, Immunology, Bioengineering, or related scientific disciplines with 3+ years experience or MS with 8+ years experience.
- 3+ years of industry experience in Cell line development is required.
- Previous experience in Cell Therapy or related field is highly preferred.
We offer competitive compensation packages, including a base salary range of $133,000, medical, dental, vision insurance, a 401(k) plan, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits.
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