Lead Immunologist Researcher Boston

4 days ago

Étreux, Hauts-de-France, United States HireMinds Full time

Senior Associate Scientist or Scientist Opportunity in Immunology Research

HireMinds Biotech is seeking an experienced Senior Associate Scientist or Scientist to join our client's discovery and preclinical efforts in immunology research. Based in Boston, MA, this role involves providing expert MOA study support, preclinical, and translational immunology experiment expertise.

About the Role

  • We are looking for a highly motivated individual with hands-on experience executing and documenting in vitro studies with primary human immune cells.
  • The successful candidate will have expertise in multicolor flow cytometry-based immunophenotyping, FACS, and cellular immunology assays.
  • This position offers opportunities to contribute to understanding disease-relevant T-cell receptor (TCR) repertoires and work on generating and interrogating TCR-transduced human cell lines and primary human T cells.

Responsibilities

  • Plan and execute in vitro/ex vivo studies using primary human immune cells from healthy donors and patients independently and efficiently.
  • Work on studies focused on immunophenotyping through multicolor flow cytometry, FACS, and cellular immunology assays.
  • Advance the company's work in isolating and transducing cell lines using cell culture with primary human/non-human PBMCs, immune cells, and T-cells.
  • Contribute to the design, construction, and testing of TCR lentiviral/retroviral vectors.
  • Conduct experiments, document data accurately, and communicate findings effectively with the project team and management.
  • Collaborate with team members to achieve experimental and organizational goals.

Requirements

  • Ph.D. in Immunology or a relevant field with ~3 years of Industry experience OR M.S. with 7+ years, or B.S. with 9+ years in industry lab positions.
  • Hands-on experience executing and documenting in vitro studies with primary human immune cells is essential.
  • Expertise in multicolor flow cytometry-based immunophenotyping, FACS, and cellular immunology assays.
  • Experience analyzing antigen-specific T cells.
  • Proficiency in molecular biology, lentiviral/retroviral vector design, synthetic biology, and assay development is preferred.
  • Hands-on experience generating stably transduced T cell lines and primary T cells.
  • Experience with B-cell studies in autoimmune diseases.
  • Self-motivation with the ability to work independently in a fast-paced environment.

Estimated Salary: $85,000 - $110,000 per year

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