Principal Scientist/Associate Director, Preclinical Research and Development

4 days ago

Cambridge, Massachusetts, United States Cullinan Therapeutics Full time
About Cullinan Therapeutics

Cullinan Therapeutics is a biopharmaceutical company dedicated to creating innovative treatments for patients. Our mission is to develop transformative therapeutics across a wide range of cancer and autoimmune indications.

Job Summary

We are seeking a highly skilled Principal Scientist/Associate Director to oversee and/or support early stage drug development projects in our pipeline. The successful candidate will lead research activities in a virtual manner, collaborating with a global network of contract research organizations and research collaborations.

Key Responsibilities
  • Lead and oversee contract research organizations in discovery efforts, including construct generation, in vitro characterization, in vivo models, and mechanistic studies.
  • Design and execute program strategy and research plans, including assay design, technical workflow management, and resource allocation.
  • Develop budget forecasts for drug development programs, including review of active contracts and long-range planning.
  • Day-to-day oversight of external research efforts, including identification of vendors, review/approval of work orders, protocol design, assay optimization, troubleshooting, data review, data analysis using biological and statistical software, and data management/organization.
  • Deliver impactful presentations to share program updates and data with colleagues, including senior leadership.
  • Oversee logistical management of Cullinan samples, including shipment/storage of materials and maintaining a running material inventory.
  • Lead internal technical discussions on preclinical programs.
  • Develop innovative strategies to move existing programs forward.
  • Lead internal innovation projects and generate ideas for new pipeline programs.
  • Routinely review relevant scientific literature and competitive landscape; attend scientific conferences.
  • Author/review regulatory submissions documents related to nonclinical IND-enabling studies.
  • Participate in diligence activities to support the evaluation of potential new assets for addition to Cullinan portfolio.
Requirements
  • 1-3 years of industry experience.
  • PhD in cancer immunotherapy, immunology, cancer biology, biological engineering, biochemistry, or a related field.
  • Experience in cancer and/or immunology research, preferably with experience in immuno-oncology, autoimmunity, and/or protein engineering.
  • Experience evaluating drug asset value propositions, either in venture capital or in the biotech industry, is preferred.
  • Innovative thinker.
  • Strong attention to detail.
  • Highly collaborative, with an interest in working within and across teams.
  • Excellent verbal and written communication skills to serve as liaison between Cullinan and contract research organizations and other outward-facing partners.
  • Ability to excel in a fast-paced work environment with focus on multiple programs in parallel.
About Us

Cullinan Therapeutics is proud to be an Equal Opportunity Employer. We are committed to creating an inclusive and diverse environment for all employees and applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation, or any characteristic protected under applicable law.

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