Senior Scientist, Vaccine Formulation Development
4 weeks ago
Vaxcyte, Inc. is seeking a highly skilled Senior Scientist to join our Formulation and Drug Product Development team. As a key member of our team, you will be responsible for leading formulation development activities for our lead product candidate, from Phase 1/2 to commercial manufacture.
Key Responsibilities:- Lead formulation activities related to process scale-up, including filter investigation and mixing system development.
- Develop and implement formulation development strategies, including stability studies for thermal, freeze/thaw, and agitation, as well as container closure system evaluation for Drug Substance and Drug Product materials.
- Collaborate with external analytical and manufacturing CMOs to enable tech transfer and implementation of processes and analytical methods.
- Apply biophysical characterization techniques to understand antigen/adjuvant interactions and optimize formulation matrix options.
- Bachelor's or Master's degree in Pharmaceutics, Chemistry, Biophysics, or Biochemistry, with >7 years of industrial experience, or PhD in a relevant field with >5 years of experience.
- Experience in manufacturing within GxP environments, either directly or through CMOs.
- Extensive experience in developing proteins, polysaccharides, and/or protein conjugate formulations for vaccines, preferably with adjuvants.
- Leadership experience, with strong scientific and managerial skills, including critical thinking, data presentation, and experiment design.
- Excellent communication and interpersonal skills, with ability to work effectively in a remote setting.
Vaxcyte, Inc. is a next-generation vaccine company developing superior and novel vaccines to prevent infectious diseases. Our pipeline includes pneumococcal conjugate vaccine candidates, and our lead vaccine candidate, VAX-24, is a preclinical, 24-valent broad-spectrum pneumococcal conjugate PCV with preclinical proof-of-concept demonstrating potential to replace the standard of care.
We are committed to improving global health by developing innovative vaccines that address unmet medical needs. If you are a motivated and experienced scientist looking for a challenging opportunity to contribute to the development of life-saving vaccines, we encourage you to apply for this exciting role.
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