Senior Formulation Scientist

3 days ago

South San Francisco, California, United States Cypress HCM Full time

Cypress HCM is seeking a highly skilled Senior Formulation Scientist to join our team. As a key member of our formulation development team, you will be responsible for executing experiments for the formulation and QC of oral and parenteral vehicles for in vivo evaluation of novel lead materials.

Key Responsibilities:

  • Execute experiments for the formulation and QC of oral and parenteral vehicles for in vivo evaluation of novel lead materials.
  • Prepare and deliver accurate formulation of test articles to achieve experimental goals.
  • Conduct solid form characterization including thermodynamic solubility, particle size, polyform characterization, melting point, salt equivalent determination, and water content analysis to advance lead compounds toward candidate nomination.
  • Work closely with experts in medicinal chemistry, DMPK, pharmacology, and technical operations to generate key data that drive understanding of ADMET properties and test article pharmacology.
  • Partner with Technical Operations and CMC teams to develop prototype formulations and processes for non-GLP pre-clinical studies in advanced research programs.
  • Operate state-of-the-art analytical instruments, such as Agilent HPLC 1260, waters LCMS, PLM, and Rigaku Miniflex XRPD.
  • Track formulation activities under tight timelines, ensuring cross-functional collaboration and accountability.

Requirements:

  • Master's with 2+ years, or Bachelor's with 5+ years of relevant experience in an academic, biotech, or pharmaceutical industry.
  • Degree in Pharmaceutics, Pharmaceutical Sciences, Chemistry, Analytical Chemistry, Biochemistry, Chemical Engineering, or related discipline.
  • Proven experience in developing and optimizing oral and/or parenteral, formulations of small molecules for the characterization of ADMET properties or in vivo pharmacology.
  • Hands-on experience with HPLC analysis, stability testing, and physicochemical property determination. Familiarity with solid form characterization techniques, including PLM, TGA, DSC, XRPD, and Dissolution preferred.
  • Strong experimental design skills for various dose formulations, along with expertise in developing methods for drug materials with low solubility.
  • Exceptional attention to details and experience in protocol writing experience for accurately recording experimental parameters and procedures.
  • Excellent communication, organization, time management, and documentation skills. Ability to work both independently and collaboratively.

  • Senior Scientist, Vaccine Formulation Development

    2 weeks ago

    San Mateo, California, United States Vaxcyte Inc Full time

    Job Title: Senior Scientist, Formulation DevelopmentVaxcyte, Inc. is seeking a highly skilled Senior Scientist to join our Formulation and Drug Product Development team. As a key member of our team, you will be responsible for leading formulation development activities for our lead product candidate, from Phase 1/2 to commercial manufacture.Key...

  • Pre-Formulation Scientist Position

    4 days ago

    South San Francisco, California, United States Cytokinetics Full time

    Pre-Formulation Scientist Job DescriptionCytokinetics is a leading biopharmaceutical company focused on developing innovative treatments for debilitating diseases affecting cardiac muscle performance. As a pioneer in muscle biology, the company is dedicated to discovering and commercializing first-in-class muscle activators and next-in-class muscle...

  • Senior Scientist in Analytical Formulation

    2 months ago

    San Diego, California, United States Enlaza Therapeutics Full time

    About Enlaza TherapeuticsEnlaza Therapeutics is a pioneering biotech firm dedicated to the advancement of innovative synthetic biology technologies aimed at developing unique biological therapies for critical health conditions.Position OverviewWe are seeking a highly skilled Senior Scientist/Principal Scientist with expertise in protein formulation and...

  • Senior Formulation Development Scientist

    4 weeks ago

    San Carlos, California, United States BioSpace, Inc. Full time

    Job SummaryVaxcyte is seeking a highly skilled and experienced Formulation Development Scientist to join our team in San Carlos, CA. As a key member of our Formulation and Drug Product Development team, you will be responsible for leading the formulation development activities across all our programs, including formulation screening, stability studies, and...

  • Research Scientist, Formulations

    1 week ago

    San Francisco, California, United States R&D Partners Full time

    R&D Partners is seeking a highly skilled Senior Research Associate, Formulations to join our team in the Drug Discovery Department. As a key member of our Analytical and Formulation Sciences team, you will be responsible for developing and implementing formulation strategies to support the discovery and development of new medicines.Key Responsibilities:*...

  • Pre-Formulation Scientist

    1 week ago

    South San Francisco, California, United States Cytokinetics Full time

    Job SummaryCytokinetics is a leading biopharmaceutical company focused on developing innovative treatments for debilitating diseases affecting cardiac muscle performance. We are seeking a highly skilled Pre-Formulation Scientist to join our research team and contribute to the development of first-in-class muscle activators and next-in-class muscle...

  • Senior Scientist/Principal Scientist, Drug Product Process Science

    4 weeks ago

    South San Francisco, California, United States Allogene Therapeutics Full time

    About Allogene TherapeuticsAllogene Therapeutics is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR TTM) products for cancer and autoimmune disease. Our mission is to deliver life-changing products for patients.Job DescriptionWe are seeking a highly motivated Senior Scientist/Principal...

  • Senior Scientist, Analytical Development Expert

    1 month ago

    South San Francisco, California, United States Meet Full time

    Senior Scientist, Analytical Development OpportunityMeet is partnering with a leading Bay Area Biotech to fill a Senior Scientist, Analytical Development position.This exciting opportunity is for a candidate with expertise in small molecule analytical development of drug substances and drug products, with strong CMC experience and CMO oversight to advance...

  • Senior Research Associate

    2 weeks ago

    South San Francisco, California, United States R&D Partners Full time

    Senior Research Associate - Formulations ExpertR&D Partners is seeking a highly skilled Senior Research Associate to join our Formulations team within Drug Discovery. As a key member of our team, you will be responsible for conducting activities related to test article formulation to support drug discovery programs.Key Responsibilities:Execute experiments...

  • Senior Research Associate

    4 weeks ago

    South San Francisco, California, United States R&D Partners Full time

    Senior Research Associate - Formulations ExpertR&D Partners is seeking a highly skilled Senior Research Associate to join our Formulations team within Drug Discovery. As a key member of our team, you will be responsible for conducting activities related to test article formulation to support drug discovery programs driving advancements in biological target...

  • Biotech Formulation Analytics Group Leader

    2 weeks ago

    South San Francisco, California, United States People With Chemistry Full time

    Exciting Opportunity for a Group Leader in Formulation AnalyticsMeet's innovative and fast-growing biotech client in San Mateo County has engaged us on an exciting new search for a talented Group Leader, Formulation Analytics.This candidate will be leading analytical method development to support Drug Product characterization, directly managing junior-level...

  • Distinguished Scientist

    3 weeks ago

    San Francisco, California, United States Zillow Full time

    About the RoleZillow is seeking a highly skilled Distinguished Scientist to join our AI & Experiences Org. As a key member of our team, you will be responsible for advancing our mission by formulating and working on science-driven initiatives related to user experiences.This is a unique opportunity to work on cutting-edge technologies that enable immersive...

  • Senior Research Scientist

    3 weeks ago

    South San Francisco, California, United States Planet Pharma Full time

    Senior Research AssistantPlanet Pharma is seeking a highly skilled and motivated Senior Research Assistant to join our Analytical and Formulation Sciences team within the Drug Discovery Department.About the RoleWe are looking for a talented individual to contribute to the discovery of novel medicines by conducting activities related to test article...

  • Senior Bioconjugation Scientist

    2 weeks ago

    South San Francisco, California, United States Global Channel Management Full time

    Bioconjugation Large Molecule Discovery RoleWe are seeking a highly skilled Senior Bioconjugation Scientist to join our team at Global Channel Management.Key Responsibilities:Design and execute experiments to develop and optimize bioconjugates using various conjugation chemistries.Collaborate with cross-functional teams to develop and implement ADC...

  • Senior Research Scientist

    2 weeks ago

    South San Francisco, California, United States Planet Pharma Full time

    Job Title: Associate ScientistPlanet Pharma is seeking a highly skilled Associate Scientist to join our team in South San Francisco, CA.About the Role:We are looking for an Associate Scientist with a strong background in Immunology, Pharmacology, Cell Biology, Molecular Biology, or a related field. The ideal candidate will have a PhD with 1+ years of...

  • Senior Scientist, Drug Product Analytics

    4 weeks ago

    San Carlos, California, United States BioSpace, Inc. Full time

    Job SummaryVaxcyte is seeking a highly skilled and experienced Senior Scientist to join our Drug Product Analytics team. As a key member of our team, you will be responsible for leading analytical method development and execution for Drug Product characterization, as well as managing a team of scientists to support process development activities, formulation...

  • Senior Research Scientist

    3 weeks ago

    South San Francisco, California, United States Planet Pharma Full time

    Senior Research AnalystThis is a unique opportunity to expand your expertise in formulation and analytical sciences while contributing to the discovery of novel medicines at Planet Pharma.Key Responsibilities:Conduct experiments for the formulation and QC of oral and parenteral vehicles for in vivo evaluation of novel lead materials.Prepare and deliver...

  • Senior Clinical Laboratory Scientist

    1 week ago

    South San Francisco, California, United States Kaiser Permanente Full time

    Job Summary:We are seeking a highly skilled Senior Clinical Laboratory Scientist to join our team at Kaiser Permanente. As a key member of our laboratory team, you will be responsible for performing pre-analytical, analytical, and post-analytical procedures and analyses to provide data for health maintenance, diagnoses, treatment, and monitoring of medical...

  • Senior Bioprocess Scientist

    4 weeks ago

    San Diego, California, United States Simply Biotech Full time

    Senior Bioprocess Scientist Job DescriptionSimply Biotech is seeking a highly skilled Senior Bioprocess Scientist to join our team in San Diego, CA. As a key member of our Bioprocess Development team, you will be responsible for developing and optimizing media and processes to support seafood cell culture.Key Responsibilities:Develop strategic approaches to...

  • Senior Formulation Development Manager

    2 weeks ago

    South San Francisco, California, United States HireMinds Full time

    About Our ClientHireMinds is a leading biotechnology company at the forefront of developing innovative non-viral gene therapy platforms.We are seeking a highly skilled and experienced Associate Director to join our research team, focusing on the strategic development, implementation, and oversight of pre-formulation, formulation development, tech transfer,...