Group Leader, Formulation Development Specialist

1 day ago

San Carlos, California, United States BioSpace, Inc. Full time
Job Title: Group Leader, Formulation Development

At Vaxcyte, we are seeking a highly skilled and experienced Group Leader, Formulation Development to join our team. As a key member of our Formulation and Drug Product Development team, you will be responsible for leading the formulation development activities across all our programs.

Key Responsibilities:
  • Lead a team of scientists to support the formulation development activities, including formulation screening, stability studies, and container closure system evaluation.
  • Play a pivotal role in supporting investigations related to quality issues, deviations, out-of-specification results, and anomalies at all stages of vaccine drug product development.
  • Apply biophysical characterization techniques to fully understand antigen/adjuvant interactions and to assess formulation matrix optimization options.
  • Coordinate day-to-day laboratory activities and experiments of the Formulation Development Group, ensuring sufficient resource coverage and performance to meet scheduled turnaround times for formulation development deliverables.
  • Identify project scientific needs and gaps, including conceptual design, planning, execution through the team, data analysis, and next-step proposal to both the DP and wider Project Team.
  • Track stability data and provide regular updates on developmental and official stability studies to ensure timely communication of findings and necessary adjustments.
  • Collaborate closely with DP management and external Vaxcyte Team members to ensure supply/demand, in vivo, DS quality, analytical methods, CMO status, and timelines are all in sync with formulation development activities to hit milestones as needed.
  • Prepare protocols and write detailed reports on formulation development activities, data analysis, and outcomes, ensuring clear communication of results and recommendations.
  • Work with external analytical and manufacturing CMOs to enable tech transfer and implementation of processes and analytical methods.
Requirements:
  • PhD in Pharmaceutics, Chemistry, Biophysics, or Biochemistry with >6 years of relevant experience or a MSc in Pharmaceutics, Chemistry, Biophysics, or Biochemistry preferred, with >10 years of industrial experience.
  • Extensive experience in developing proteins, polysaccharides, and/or protein conjugates formulations for vaccines, preferably vaccine systems containing adjuvants.
  • Proficient in using biophysical and calorimetric techniques for proteins and protein-polysaccharide conjugates, including Circular Dichroism, Fourier Transform Infrared (FTIR) Spectroscopy, Fluorescence Spectroscopy, Differential Scanning Calorimetry (DSC), and Isothermal Titration Calorimetry (ITC).
  • Experience in leading stability studies and investigating quality issues, deviations, out-of-specification results, along with using DoE for complex system optimization is required.
  • Experience of manufacturing within GxP environments either directly or through CMOs.
  • Ability to move and multitask seamlessly between complex programs and project teams is required.
  • Experience in management of junior scientists is strongly preferred, with a desire to continue in a managerial/leadership setting.
What We Offer:
  • A competitive compensation package, including comprehensive benefits and an equity component.
  • A dynamic and collaborative work environment with a team of experienced professionals.
  • Opportunities for professional growth and development in a rapidly evolving industry.
How to Apply:

Interested candidates should submit their application, including a cover letter and resume, to [insert contact information].

  • Biotech Formulation Analytics Group Leader

    1 day ago

    South San Francisco, California, United States People With Chemistry Full time

    Exciting Opportunity for a Group Leader in Formulation AnalyticsMeet's innovative and fast-growing biotech client in San Mateo County has engaged us on an exciting new search for a talented Group Leader, Formulation Analytics.This candidate will be leading analytical method development to support Drug Product characterization, directly managing junior-level...

  • Senior Formulation Development Scientist

    3 weeks ago

    San Carlos, California, United States BioSpace, Inc. Full time

    Job SummaryVaxcyte is seeking a highly skilled and experienced Formulation Development Scientist to join our team in San Carlos, CA. As a key member of our Formulation and Drug Product Development team, you will be responsible for leading the formulation development activities across all our programs, including formulation screening, stability studies, and...

  • Scientific Formulation Specialist

    1 month ago

    South San Francisco, California, United States Planet Pharma Full time

    Job Title: Scientific Formulation Specialist Job Summary: Planet Pharma is seeking a highly skilled Scientific Formulation Specialist to join our team. As a key member of our pharmaceutical development team, you will be responsible for formulating liquid and lyophilized protein therapeutics, preparing formulation and assay buffers, as well as containers...

  • Senior Analytical Development Leader

    10 hours ago

    San Carlos, California, United States BioSpace, Inc. Full time

    Job SummaryWe are seeking a highly skilled and experienced Senior Analytical Development Leader to join our team at Vaxcyte, Inc. in San Carlos, CA. The successful candidate will lead a team of 4-5 analysts in conducting RD stability studies, assay control qualification, and characterization testing.Key ResponsibilitiesManage R&D ADQC stability programs,...

  • Senior Formulation Development Manager

    1 day ago

    South San Francisco, California, United States HireMinds Full time

    About Our ClientHireMinds is a leading biotechnology company at the forefront of developing innovative non-viral gene therapy platforms.We are seeking a highly skilled and experienced Associate Director to join our research team, focusing on the strategic development, implementation, and oversight of pre-formulation, formulation development, tech transfer,...

  • Senior Scientist, Vaccine Formulation Development

    14 hours ago

    San Mateo, California, United States Vaxcyte Inc Full time

    Job Title: Senior Scientist, Formulation DevelopmentVaxcyte, Inc. is seeking a highly skilled Senior Scientist to join our Formulation and Drug Product Development team. As a key member of our team, you will be responsible for leading formulation development activities for our lead product candidate, from Phase 1/2 to commercial manufacture.Key...

  • Practice Group Marketing Specialist

    3 weeks ago

    San Francisco, California, United States SourcePro Search, LLC Full time

    Job Title: Practice Group Marketing SpecialistAt SourcePro Search, LLC, we are seeking a highly skilled Practice Group Marketing Specialist to join our team. As a key member of our marketing team, you will play a critical role in supporting the business development and marketing activities for our practice groups.Key Responsibilities:Develop and implement...

  • Group Leader

    1 day ago

    San Marcos, California, United States San Marcos USD Full time

    About the EmployerWelcome to San Marcos Unified School District, a forward-thinking community that fosters exceptional educational experiences. Our collaborative environment empowers students to excel and reach their full potential.Job SummaryWe are seeking a dedicated Group Leader to join our team at San Elijo Elementary School. This part-time position...

  • Formulation Chemist

    1 month ago

    San Jose, California, United States Element Solutions Full time

    Unlock Your Potential as a Formulation ChemistAt Element Solutions, we're committed to revolutionizing the electronics industry with innovative materials and technologies. As a Formulation Chemist, you'll play a critical role in developing cutting-edge solutions that drive efficiency and performance.Key Responsibilities:Design and execute experimental plans...

  • Formulation Chemist

    3 weeks ago

    San Jose, California, United States Element Solutions Full time

    Unlock Your Potential as a Formulation ChemistAt Element Solutions, we're revolutionizing the electronics industry with innovative materials and technologies. As a Formulation Chemist, you'll play a crucial role in developing cutting-edge solutions that drive efficiency and performance.Key Responsibilities:Design and execute experimental plans to test new...

  • Formulation Manager

    4 weeks ago

    San Francisco, California, United States Lifestyle Brands LLC Full time

    About the RoleLifestyle Brands LLC is a dynamic and innovative company that is part of the SC Johnson family. We are seeking a highly skilled and motivated individual to join our team as an Associate Manager, Formulation. In this role, you will be responsible for formulating and commercializing sustainable and cost-effective products that meet our consumer...

  • Formulation Chemist

    2 weeks ago

    San Jose, California, United States Element Solutions Full time

    Unlock Your Potential as a Formulation ChemistAt Element Solutions, we're revolutionizing the electronics industry with innovative materials and technologies. As a Formulation Chemist, you'll play a crucial role in developing cutting-edge solutions that drive efficiency and performance.Key Responsibilities:Design and execute experimental plans to test new...

  • ASES Group Leader

    10 hours ago

    San Diego, California, United States Boys & Girls Clubs of Greater San Diego Full time

    Job Title: ASES Group LeaderJoin the Boys & Girls Clubs of Greater San Diego team as an ASES Group Leader and make a positive impact on the lives of youth in our community!Job Summary:The ASES Group Leader will provide virtual and classroom instruction, assistance, and tutoring to students in the after-school program. This role will lead engaging culturally...

  • Formulation Manager

    4 weeks ago

    San Francisco, California, United States SC Johnson Full time

    About the RoleWe are seeking an experienced Associate Manager to join our Formulation team at SC Johnson. As a key member of our team, you will be responsible for formulating and commercializing sustainable and cost-effective products.Key ResponsibilitiesDevelop new formulations and line extensions using green chemistry tools that meet our consumer and...

  • Executive Director, Formulation Business Development

    1 month ago

    San Diego, California, United States Debut Biotech Full time

    About Debut BiotechWe are seeking a seasoned professional to lead the growth of our formulation business in the biotech and beauty industry. Our company, Debut Biotech, is dedicated to creating high-performing, sustainable beauty products that utilize biotech for product innovation.Key ResponsibilitiesBusiness Development: Grow the formulations business to...

  • Formulation Manager

    4 weeks ago

    San Francisco, California, United States SC Johnson Full time

    About the RoleWe are seeking an experienced Associate Manager to join our Formulation team at SC Johnson. As a key member of our team, you will be responsible for formulating and commercializing sustainable and cost-effective products.Key ResponsibilitiesDevelop new formulations and line extensions using green chemistry tools that meet our consumer and...

  • Formulation Manager

    14 hours ago

    San Francisco, California, United States SC Johnson Full time

    About the RoleWe are seeking an experienced Associate Manager to join our Formulation team at SC Johnson. As a key member of our team, you will be responsible for formulating and commercializing sustainable and cost-effective products.Key ResponsibilitiesDevelop new formulations and line extensions using green chemistry tools that meet our consumer and...

  • Senior Quality Control Specialist

    3 weeks ago

    San Carlos, California, United States The Steely Group Full time

    {"title": "Senior Quality Control Specialist", "content": "Job SummaryThe Steely Group is seeking a highly skilled Senior Quality Control Specialist to support the daily operations of our Quality Control group. As a key member of our team, you will be responsible for ensuring the quality and integrity of our products.Key ResponsibilitiesSupport sampling and...

  • Senior Quality Control Specialist

    3 weeks ago

    San Carlos, California, United States The Steely Group Full time

    Job OverviewWe are seeking a highly skilled and detail-oriented Senior Quality Control Specialist to join our Quality Control team. As a key member of our team, you will be responsible for supporting the daily operations of the Quality Control group, while contributing to the development of new processes that maximize our technology and enhance our internal...

  • Senior Quality Control Specialist

    4 weeks ago

    San Carlos, California, United States The Steely Group Full time

    Job Title: Senior Quality Control SpecialistWe are seeking a highly skilled Senior Quality Control Specialist to support the daily operations of our Quality Control group. As a key member of our team, you will be responsible for ensuring the quality and integrity of our products.Responsibilities:Support sampling and testing of incoming raw materials to...