Postdoctoral Research Scientist

1 week ago


New York, New York, United States Columbia University Full time
Postdoctoral Research Scientist Opportunity

Columbia University Vagelos College of Physicians and Surgeons is seeking a highly motivated Postdoctoral Research Scientist to contribute to our research team.

Under the supervision of the Principal Investigator, the individual will train in developing and participating in a research project that focuses on cellular and molecular mechanisms underlying neuronal degeneration relevant to basic and translational studies in novel transgenic mouse models of aging and Alzheimer's disease.

Key Responsibilities:
  • Conduct laboratory research in the area of neurodegeneration and mitochondrial function, with a focus on cellular and molecular mechanisms.
  • Perform cell and neuronal culture, transfection of gene expression in primary and continuous cell lines, viral transfections in vitro and in vivo, and mouse brain injection.
  • Immunostaining/fluorescence and confocal microscopy images and neuropathology in vitro cultured neurons and in vivo brain sections.
  • Immunoblotting, ELISA, and RNA analysis for protein expression and pattern and gene changes, and mouse behavior.
  • Conduct literature searches, manage data, analyze experimental results, and publish data. Participate in the development of an extramurally funded research program by assisting PIs with research grants.
Requirements:
  • PhD, MD, or MD/PhD degree
  • Experience in biochemistry and molecular biology
  • Participation in research projects related to mitochondrial function and structure changes
  • Previous experience with immunostaining, neuronal culture, confocal microscopy
  • The ability to assist with writing scientific papers and research grants


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