Senior Principal Scientist

4 days ago

San Diego, California, United States Pfizer Full time

Pfizer's Oncology Research Unit (ORU) in La Jolla, California, is seeking a Senior Principal Scientist (PhD) to join the Tumor Immunity team focused on delivering breakthroughs that change patients' lives by redirecting the immune system against cancer.

The Senior Principal Scientist will be responsible for driving scientific strategies and their implementation within a collaborative team of motivated and rigorous scientists to advance immuno-oncology programs within our pre-clinical portfolio.

Key Responsibilities:

  • Lead research project teams to develop and execute on research strategy and development objectives aligned with ORU strategic focus areas
  • Provide scientific leadership to preclinical project teams serving as the biology lead to design, plan, and execute laboratory experiments and deliver high-quality decision-making data sets in support of project objectives and timelines
  • Foster and maintain strong collaborative relationships across the ORU discovery organization to design experiments and interpret data sets, driving pipeline advancements
  • Strengthen department's overall immuno-oncology capabilities and expertise by employing innovative methods and technologies to test therapeutic hypotheses
  • Present research findings and share learnings at research project team meetings and research forums and support the development of team members in these settings
  • Manage and mentor scientists in both laboratory based and discipline leadership roles to support preclinical discovery research programs within a matrixed environment
  • Actively contribute to preparation of required drug development and regulatory documents (e.g., IND submissions), with responsibilities for non-clinical pharmacology data packages
  • Effectively communicate program strategy, methodology, progress, and challenges to multiple stakeholders and partners, including senior executives and governance committees

Requirements:

  • PhD in immunology, cancer biology or relevant biological science with 8+ years of relevant postdoctoral experience
  • Must have industry experience leading projects through discovery process
  • Scientific expertise in immuno-oncology including previous experience with characterization and preclinical development of T and/or NK cell engagers
  • Strong verbal and written communication skills
  • Leadership experience and capabilities including the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact
  • Demonstrated success in team management of PhD and non-PhD level scientists, in particular lab based colleagues

What We Offer:

  • Annual base salary range: $117,300.00 to $195,000.00
  • Bonus target: 17.5% of base salary
  • Eligibility to participate in our share-based long-term incentive program
  • Comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments

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