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Research Scientist II/Senior Research Scientist, Downstream Process Development

4 weeks ago

Cambridge, Massachusetts, United States Repertoire Immune Medicines Full time

h3JobOverview/h3pWeareseekingahighlyskilledResearchAssociateII/SeniorRAtosupportdownstreamproductionandprocessdevelopmentofTCRbispecificsandMHCproteinsonourProteinEngineeringandMolecularSciencesteam./ph3KeyResponsibilities/h3ulliOptimizeproteinrefoldingconditionsfrominclusionbodiestoproducehigh-qualityproteins./liliDevelopandimplementrobustprocessesforproteinpurificationusingvariouschromatographytechniques,includingimmobilizedmetalaffinity,ion-exchange,andsizeexclusionchromatography./liliExecuteenzymaticandchemicalproteinmodificationprotocolstoenhanceproteinfunctionandstability./liliCharacterizerecombinantproteinsusingvariousbiochemicalandbiophysicalassays,includingSDS-PAGE,Westernblot,proteinquantitation,HPLC,ELISA,andOctet./liliPresentdataandresultstotheteamandmanagementinaclearandconcisemanner./li/ulh3Requirements/h3ulliBS/MSinBiochemistry,Biology,Bioengineering,Immunology,orarelatedfield./lili2+yearsoflaboratoryexperienceinproteinpurification,proteinrefolding,andproteinmodification./liliStrongorganizationalandcommunicationskills,withtheabilitytoworkeffectivelyinateamenvironment./li/ulpRepertoireImmuneMedicinesisabiotechnologycompanydedicatedtounlockingthepowerofthehumanimmunesystemtotreatcancerandautoimmunedisease.Wearecommittedtodiversity,equity,andinclusionintheworkplaceandstrivetocreateaculturethatvaluesandrespectsthecontributionsofallemployees./p