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Biologics Production and Analytics Scientist
2 months ago
About Fable Therapeutics:
We are a discovery-stage biotechnology company that develops purpose-built biologics to overcome therapeutic index limitations and channel therapeutic response where and when it matters.
Our team is powered by state-of-the-art structure and sequence-based protein language models, and we are backed by a 2024 $40M Series A investment co-led by Versant Ventures and DCVC.
We are seeking a highly talented and motivated scientist to join our growing team and establish our in-house Biologics production and analytics capabilities.
Key Responsibilities:
- Production of antibody-based constructs and libraries from AI designed sequences
- Molecular Biology, transient transfection of mammalian cell culture, and antibody production, with high-throughput capabilities
- Purification of antibody constructs by affinity chromatography, IEX and other methods on FPLC, and with automation in a high-throughput manner
- Binding assays based on FACS, flow cytometry and ELISA
- Biophysical high throughput characterization (for example SEC, HIC, DSC, DSF, AC-SINS, cIEF) of candidate therapeutic proteins
- Careful documentation and record-keeping of scientific results
- Molecule registration and inventory, and data upload to databases and LIMS systems
- Curation of data for ingestion and utilization by ML scientists
About You:
- BA in Molecular Biology or Protein Science and 4+ years industry experience in biologics discovery and protein science OR MSc and 2+ years experience
- Excellent molecular biology and protein science skills
- Familiarity with liquid handling systems and high-throughput systems
- Committed to digital workflows and the lab of the future
- Ability to work efficiently in a close-knit team and deliver high quality, reproducible data in a fast-paced environment
- Attentive to detail and a careful experimenter
- Ability to take initiative and improve processes
- An excellent communicator and presenter of scientific data
- Passionate about the power of AI to transform biotherapeutics
- Focused on quantifiable results and data driven decisions
- Collaborative and inclusive mindset
We are an equal opportunity employer and we value diversity and inclusion. Fable Therapeutics provides an open, collegial, and friendly work environment where we empower people and provide them with opportunities to develop their long-term careers.
