Process Optimization Engineer

2 weeks ago


Rockville, Maryland, United States System One Full time

Position:

Process Development Engineer

Location:
Rockville, MD

Schedule:
Monday to Friday, 8 AM to 5 PM

Employment Type:
Contract with potential for permanent placement based on performance

Overview:

Our client, a dynamic entity in the field of synthetic biology and immunological drug innovation, is dedicated to the advancement of novel cellular-based immune therapies. They are at the forefront of developing biologics that utilize a proprietary oral delivery system.

Their research is propelled by groundbreaking discoveries related to the microbiome, which facilitate the creation of targeted immune-modulatory therapies aimed at addressing conditions such as inflammation, autoimmunity, cancer, and infectious diseases.

We are currently seeking a skilled development engineer with expertise in bacterial fermentation to join their laboratory team in Rockville, Maryland. This role presents an exceptional opportunity for innovative scientists to enhance their skills and gain invaluable experience within the biotechnology sector.


Key Responsibilities:

- Design and execute experiments, manage laboratory-scale processes, and present findings in internal discussions while contributing to the development of process strategies.

- Independently conduct bioreactor operations and purification processes to refine, optimize, and scale fermentation and purification techniques.

- Develop expertise in specialized scientific areas, including bacterial scale-up, freeze-drying, and spore development.

- Present data in internal meetings, collaborate with research teams, and produce scientific documentation for both internal and external use.

- Author and oversee master batch records, standard operating procedures (SOPs), and policy documents.

- Contribute to the preparation of Investigational New Drug applications (INDs), regulatory updates, and grant reports.


Qualifications:
- Advanced degree (MS and/or PhD) in chemical engineering, biochemistry, microbiology, or related fields.
- 1-4 years of direct experience in process development or bacterial fermentation.
- Proficiency in operating small to medium-scale bioreactors with a focus on bacterial fermentation.
- Experience in optimizing bacterial growth, freeze-drying, and related processes.
- Familiarity with anaerobic microbiology and spore biology is preferred but not mandatory.
- Background in yeast and mammalian cell cultures is a plus.
- Experience in bench-scale protein purification and proficiency with statistical tools such as JMP.
- Understanding of good manufacturing practices (GMP) is essential.
- Ability to thrive in a collaborative, fast-paced team environment.

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