Research Scientist
3 days ago
We are seeking a highly skilled and motivated Research Fellow to join our team at Brigham and Women's Hospital (BWH). As a Research Fellow, you will be responsible for conducting cutting-edge research in analytical chemistry, with a focus on bioanalytical method development and validation.
Key Responsibilities:- Develop and validate bioanalytical methods for HPLC, LCMS, ELISA, qPCR, and ICP-MS in complex matrices.
- Design and implement automated liquid handling programs for bioanalytical sample preparation.
- Validate bioanalytical methods and evaluate results against internal and FDA/ICH guidelines.
- Prepare pre-clinical LCMS and GCMS samples with high precision and quality.
- Operate LCMS, ELISA, PCR, GCMS, and ICP-MS equipment to analyze pre-clinical samples.
- Troubleshoot and repair analytical instrumentation, and/or coordinate onsite repair from OEM service provider.
- Train lower-level staff, students, and scientists on bioanalytical techniques and help various programs design their experiments for successful analytical outcomes.
- Assist in evaluating new capital assets and equipment for the bioanalytics team.
- Write and prepare standard operating procedures.
- Support lead analytical chemist with requests, as needed.
- Manage sample tracking in LIMS.
- Document daily tasks and upload files to ELN.
- Help enforce EH&S guidelines amongst team.
- Ph.D. in chemistry (analytical or organic), or related field.
- Demonstrated track-record of successful analytical chemistry research or experience in a research environment.
- Track record of successful project management, ability to work independently and as part of a team, strong time management skills, and ability to self-problem solve.
- Strong background in organic chemistry and biochemistry.
- Bioanalytical assay development (HPLC, LCMS, immunological assays).
- Chromatography (HPLC, LC, CE).
- Mass spectrometry (LCMS, LC-MS/MS, LC-HRMS, GC-MS).
- ELISA and AlphaLISA.
- Electrophoresis.
- PCR and qPCR.
We are looking for a highly motivated and organized individual with a strong background in analytical chemistry and bioanalytical method development. The ideal candidate will have experience with the above techniques and tools, as well as a strong publication history in peer-reviewed journals.
Candidate must have self-motivation and willingness to learn new tools and techniques; strong organizational, interpersonal, and communication skills; ability to work independently and as part of a team; comfort summarizing and reporting results to interdisciplinary researchers; commitment to exceeding standards and producing accurate, high-quality work; meticulous attention to detail; practiced documentation skills; and ability to follow safety procedures and maintain a safe work environment.
BWH is an Affirmative Action Employer. We are committed to diversity and inclusion and welcome applications from qualified candidates of all backgrounds.
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