Research Scientist

3 days ago

Cambridge, Massachusetts, United States Brigham & Women's Hospital(BWH) Full time
Job Title: Research Fellow

We are seeking a highly skilled and motivated Research Fellow to join our team at Brigham and Women's Hospital (BWH). As a Research Fellow, you will be responsible for conducting cutting-edge research in analytical chemistry, with a focus on bioanalytical method development and validation.

Key Responsibilities:
  • Develop and validate bioanalytical methods for HPLC, LCMS, ELISA, qPCR, and ICP-MS in complex matrices.
  • Design and implement automated liquid handling programs for bioanalytical sample preparation.
  • Validate bioanalytical methods and evaluate results against internal and FDA/ICH guidelines.
  • Prepare pre-clinical LCMS and GCMS samples with high precision and quality.
  • Operate LCMS, ELISA, PCR, GCMS, and ICP-MS equipment to analyze pre-clinical samples.
  • Troubleshoot and repair analytical instrumentation, and/or coordinate onsite repair from OEM service provider.
  • Train lower-level staff, students, and scientists on bioanalytical techniques and help various programs design their experiments for successful analytical outcomes.
  • Assist in evaluating new capital assets and equipment for the bioanalytics team.
  • Write and prepare standard operating procedures.
  • Support lead analytical chemist with requests, as needed.
  • Manage sample tracking in LIMS.
  • Document daily tasks and upload files to ELN.
  • Help enforce EH&S guidelines amongst team.
Qualifications:
  • Ph.D. in chemistry (analytical or organic), or related field.
  • Demonstrated track-record of successful analytical chemistry research or experience in a research environment.
  • Track record of successful project management, ability to work independently and as part of a team, strong time management skills, and ability to self-problem solve.
  • Strong background in organic chemistry and biochemistry.
  • Bioanalytical assay development (HPLC, LCMS, immunological assays).
  • Chromatography (HPLC, LC, CE).
  • Mass spectrometry (LCMS, LC-MS/MS, LC-HRMS, GC-MS).
  • ELISA and AlphaLISA.
  • Electrophoresis.
  • PCR and qPCR.

We are looking for a highly motivated and organized individual with a strong background in analytical chemistry and bioanalytical method development. The ideal candidate will have experience with the above techniques and tools, as well as a strong publication history in peer-reviewed journals.

Candidate must have self-motivation and willingness to learn new tools and techniques; strong organizational, interpersonal, and communication skills; ability to work independently and as part of a team; comfort summarizing and reporting results to interdisciplinary researchers; commitment to exceeding standards and producing accurate, high-quality work; meticulous attention to detail; practiced documentation skills; and ability to follow safety procedures and maintain a safe work environment.

BWH is an Affirmative Action Employer. We are committed to diversity and inclusion and welcome applications from qualified candidates of all backgrounds.

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