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Senior Vice President of Biological Research
2 months ago
The Senior Vice President of Biological Research is tasked with directing all biological and pharmacological research and development initiatives, spearheading innovative projects, and upholding the highest standards of scientific integrity. This executive position is crucial in defining and steering the scientific trajectory of our research endeavors, managing a team of proficient scientists, and propelling our therapeutic candidate pipeline forward. The ideal candidate will possess a robust history of leveraging profound knowledge in cancer biology and biological sciences to discover and advance molecules towards IND and optimal clinical development.
Key Responsibilities:
Leadership and Oversight:
- Guide, mentor, and supervise a team of scientists and researchers within the Biology and Pharmacology division
- Encourage a collaborative and innovative research atmosphere that promotes creativity and scientific excellence
- Formulate and execute strategic plans for the department, ensuring alignment with the company’s overarching goals and objectives
- Oversee all biological and pharmacological research initiatives, ensuring they are conducted with scientific rigor and ethical standards
- Identify and prioritize new research avenues and projects that resonate with the company’s mission
- Drive the development and validation of novel biological assays, technologies, and products
- In addition to providing strategic oversight, actively engage in the advancement of research programs
- Work alongside other departments, including Chemistry, Non-Clinical Development, CMC, Clinical, and G&A to ensure cohesive project development and execution
- Articulate research findings and progress to senior management, stakeholders, and external partners
- Represent the organization at scientific conferences, industry events, and in scholarly publications
- Develop and manage the department's budget, resources, and equipment efficiently
- Ph.D. in Biological Sciences, Biochemistry, Molecular Biology, Pharmacology, or a related discipline
- A minimum of 12 years of experience in the biotech or pharmaceutical sector, with at least 5 years in a leadership capacity
- Demonstrated success in managing and leading small-molecule oncology projects from discovery through IND
- Comprehensive knowledge of current trends and advancements in biological sciences and biotechnology
- Strong expertise in molecular biology, cell biology, pharmacology, pharmacodynamics, and related fields
- Extensive understanding of key components of drug discovery, including drug metabolism, pharmacokinetics, toxicology, and structural biology
- Exceptional problem-solving, analytical, and strategic thinking abilities
- Outstanding communication and interpersonal skills, with the capability to collaborate effectively across disciplines
- Familiarity with regulatory requirements and compliance in the biotech industry
- Experience in the dynamic environment characteristic of small biotech firms is preferred
OnKure, Inc. is a clinical-stage biopharmaceutical organization dedicated to the discovery and development of best-in-class precision medicines targeting biologically validated drivers of cancers that lack adequate treatment options. Utilizing a proven structure-based drug design platform, OnKure is building a robust pipeline of tumor-agnostic candidates aimed at achieving optimal efficacy and tolerability. OnKure is currently advancing OKI-219, a selective PI3K?H1047R inhibitor, as its lead program. OnKure aspires to be a leader in targeting oncogenic PI3K? and has multiple initiatives designed to enable best-in-class targeting of this pivotal oncogene.
To attract top-tier talent, OnKure provides a competitive compensation and benefits package that includes attractive pay, performance-based bonuses, stock options, comprehensive insurance coverage (health, dental, life, and disability), self-managed paid time off, and a 401(k) plan with company matching.
OnKure is an equal opportunity employer and welcomes all job applicants. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, protected veteran status, disability, or any other protected factors.
