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Head of Bioinformatics

4 months ago

San Diego, United States Alida Biosciences Full time
Head of Bioinformatics

Alida Biosciences is an early-stage, VC backed startup company in San Diego focused on developing novel analysis tools for the detection of epigenomic markers in RNA. The company's mission is advancing the general understanding of gene regulation, discovering epigenetic drug targets and enabling next-gen RNA-based therapies.

Alida Biosciences is seeking a technically strong computational scientist with excellent leadership skills to join our team in its mission to transform omics with next-generation technologies. Leveling will be commensurate with the candidate's experience.

As an early-stage company, we offer exceptional opportunities for our employees to engage in project management, cross-functional roles, grow with the company, build new technologies, and launch innovative products.

Responsibilities
  • Leading a team of computational scientists
  • Contributing to company product roadmap
  • Representing bioinformatics at board meetings
  • Developing algorithms to advance the analysis of novel forms of genomic data
  • Creating computational pipeline components, workflows, and infrastructure to facilitate data analysis and interpretation
  • Evaluating algorithm performance and identifying opportunities for improvement
  • Analyzing experimental data and creating actionable insights and data visualizations

Requirements
• PhD in Computer Science, Computational Biology or related discipline with 8+ years of industry experience
• Understanding of NGS technology and assay development
• Familiarity with standard bioinformatics data formats and command-line tools (such as samtools, bedtools, bcftools, seqtk) and pipeline frameworks (Nextflow, snakemake, Cromwell)
• Experience writing software in Python (including numpy, pandas, matplotlib, scipy, scikit-learn, pysam) as well as experience using a strongly typed language (e.g., C++, Java, Rust, etc.)
• Strong background in quantitative reasoning, probability, and statistical inference
• Familiarity with statistical principles of experimental design
• Experience creating algorithms and developing computational models
• Experience with software development and testing, including version control (e.g., git), unit testing and continuous integration
• Experience analyzing complex experimental data and visualizing and presenting results
• Experience with the Linux command line, HPC (SLURM, SGE), containers, and cloud computing
• Prior experience in leading technical projects and teams
• Demonstrated product development experience for either internal or external facing software
• Strong oral and written communication skills

Benefits

We offer a competitive and comprehensive employee benefits package including medical, dental, and vision, LTD, paid vacation, 401k and a stock plan.

Alida Biosciences is an Equal Opportunity Employer. We do not discriminate in recruitment, hiring, training, promotion, or other employment practices for reasons of race, color, religion, gender, pregnancy, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.