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Scientist - post candidate research - Oncology Research Unit
1 month ago
Scientist - post candidate research - Oncology Research Unit We’re in relentless pursuit of breakthroughs that change patients’ lives. We innovate every day to make the world a healthier place. To fully realize Pfizer’s purpose – Breakthroughs that change patients’ lives – we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals. Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. What You Will Achieve As a Scientist, in the oncology research unit (ORU) organization, you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to develop breakthrough therapies. You will be part of a team that is addressing the critical task to support research of Oncology and Immuno-Oncology programs entering the candidate stage and proceeding into the clinic. You will contribute to the generation of data packages to support regulatory filings and studies designed to broaden our understanding of the target biology, the molecule's mechanism of action (MoA) and the tumor's mechanism of resistance. You will be an essential member of this team and creatively design and execute key experiments to address the basic and translational biology of novel drug targets, their molecular pathways, and their connection to human disease. With your deep knowledge in the discipline, and technical expertise, you will be an active team member who influences at the project team level. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience and consulting others. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide your team members. It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe. How You Will Achieve It Contribute to achievement of goals of the team and influence at the work group/project team level. Apply technical skills, scientific and functional knowledge to projects/assignments within own work group/project team independently and proactively. Perform laboratory experiments to help establish robust disease biology, biochemical and cell-based compound screening assays and carry out in vivo evaluation across a broad array of target classes for the project teams. Prepare and present experimental results to project teams. Comply with all safety training and good laboratory practices. Qualifications Must-Have Bachelor's degree in biology and 6+ years of relevant experience in the Academic/biotech/pharmaceutical industry Master's degree in molecular and cellular biology and 4+ years of relevant experience in the Academic/biotech/pharmaceutical industry Solid understanding of concepts and principles of molecular, cellular, cancer, and immune biology. In-depth, hands-on experience with mammalian and immune cell culture establishment, expansion, and characterization. Experience with genetic modification: viral vector-based transduction, electroporation/transfection Experience in cellular and immune cell-based analytics and assay development including, but not limited to, fluorescent microscopy, flow-cytometry/sorting, cell labeling, cell proliferation assays, cytotoxicity assays, and ELISA. Ability to troubleshoot, interpret, and summarize scientific data in an accurate, critical, and concise manner. Ability to communicate effectively with colleagues at all levels. Excellent communication skills, both written and oral. Must be goal-oriented with the ability to handle multiple tasks and to prioritize. Nice-to-Have Experience with biological therapies for cancer treatment Experience with antibody drug conjugate (ADC) therapeutics is highly desired Experience with high throughput and automated lab equipment and assays Experience with electronic notebook recording PHYSICAL/MENTAL REQUIREMENTS Lifting, sitting, standing, walking, bending, ability to perform laboratory work and ability to perform complex data analysis. Additional Information: Eligible for Employee Referral Work Location: On Premise Last Day to Apply: August 10, 2024 #J-18808-Ljbffr
