Current jobs related to Principal Scientist, Immunopeptidomics - Cambridge - Johnson & Johnson

  • Principal Scientist

    2 months ago


    Cambridge, Massachusetts, United States Nuvalent, Inc Full time

    Reporting to the VP, Medicinal Chemistry, the Principal Scientist, Medicinal Chemistry will have strong technical and problem-solving skills in organic and medicinal chemistry skills.The scientist in this position will work with the Nuvalent team, including the scientific founder, and will be responsible for leading medicinal chemistry efforts on at least...

  • Principal Scientist

    2 weeks ago


    Cambridge, Massachusetts, United States Novartis Group Companies Full time

    Job SummaryWe are seeking an experienced Senior Principal Scientist or Principal Scientist to join our Oncology Research and Development team at Novartis Group Companies. The successful candidate will be responsible for developing and implementing pharmacokinetics and clinical pharmacology strategies to support the development of innovative medicines.Key...

  • Principal Scientist

    2 weeks ago


    cambridge, United States Planet Pharma Full time

    Principal Scientist, Protein Production & Process DevelopmentPriority Must Haves:Refolded E. coli experience (Ideal)If no E. Coli experience, must haveExperience w/ Recombinant proteinExperience with bispecific protein productsStrong process development backgroundTech Transfer experience - working with CDMOStrong Communication and Leadership experience. Must...

  • Principal Scientist

    2 weeks ago


    Cambridge, United States Planet Pharma Full time

    Principal Scientist, Protein Production & Process DevelopmentPriority Must Haves:Refolded E. coli experience (Ideal)If no E. Coli experience, must haveExperience w/ Recombinant proteinExperience with bispecific protein productsStrong process development backgroundTech Transfer experience - working with CDMOStrong Communication and Leadership experience. Must...

  • Principal Scientist

    5 days ago


    cambridge, United States Planet Pharma Full time

    Principal Scientist, Protein Production & Process DevelopmentPriority Must Haves:Refolded E. coli experience (Ideal)If no E. Coli experience, must haveExperience w/ Recombinant proteinExperience with bispecific protein productsStrong process development backgroundTech Transfer experience - working with CDMOStrong Communication and Leadership experience. Must...

  • Principal Scientist

    1 month ago


    Cambridge, United States Planet Pharma Full time

    Principal Scientist, Protein Production & Process DevelopmentPriority Must Haves:Refolded E. coli experience (Ideal)If no E. Coli experience, must haveExperience w/ Recombinant proteinExperience with bispecific protein productsStrong process development backgroundTech Transfer experience - working with CDMOStrong Communication and Leadership experience. Must...

  • Principal Scientist

    4 weeks ago


    Cambridge, United States Planet Pharma Full time

    Principal ScientistLocation: Cambridge, MASalary: $160-180K + equity Open to relocation within the Northeast.Required Skills: Expertise in downstream processing.Experience with microbial and mammalian systems.Experience in refolding E. coli proteins is highly desirable.If E. coli experience is not available, candidates must have experience with recombinant...

  • Principal Scientist

    4 weeks ago


    Cambridge, United States Planet Pharma Full time

    Principal ScientistLocation: Cambridge, MASalary: $160-180K + equity Open to relocation within the Northeast.Required Skills: Expertise in downstream processing.Experience with microbial and mammalian systems.Experience in refolding E. coli proteins is highly desirable.If E. coli experience is not available, candidates must have experience with recombinant...


  • Cambridge, United States DeepRec.ai Full time

    Principal Machine Learning Scientist (Large Language Models)Location: Hybrid in Cambridge, Massachusetts, USADeepRec.ai seeks a dedicated Principal level Machine Learning Scientist specializing in Large Language Models (LLMs), to join our client's innovative team in Cambridge, Massachusetts.You will be part of an agile, cross-functional team responsible for...


  • Cambridge, United States DeepRec.ai Full time

    Principal Machine Learning Scientist (Large Language Models)Location: Hybrid in Cambridge, Massachusetts, USADeepRec.ai seeks a dedicated Principal level Machine Learning Scientist specializing in Large Language Models (LLMs), to join our client's innovative team in Cambridge, Massachusetts.You will be part of an agile, cross-functional team responsible for...


  • Cambridge, Massachusetts, United States DeepRec Full time

    Job Title: Principal NLP Machine Learning ScientistAbout the Role:We are seeking a highly skilled Principal Machine Learning Scientist to join our team at DeepRec. As a key member of our team, you will be responsible for developing and training large-scale language models, fine-tuning models with feedback, and integrating multimodal scientific data.Key...

  • Principal Scientist

    1 week ago


    Cambridge, Massachusetts, United States Bristol-Myers Squibb Full time

    About the RoleBristol-Myers Squibb is seeking a highly skilled Principal Scientist to join our Computational Design and Predictive Modeling team in Cambridge, MA. As a key member of our team, you will play a critical role in developing novel bioinformatics and machine learning solutions to analyze and characterize antibody repertoire sequencing data.Key...


  • Cambridge, Massachusetts, United States Newton Colmore Full time

    About the RoleWe are seeking a highly experienced Senior DMPK and ADME Expert to join our research team at Newton Colmore. As a Principal Scientist in Drug Development, you will play a key role in designing and implementing in vivo PK studies, providing updates and results to research teams, and presenting strategies at governance interactions.Key...


  • cambridge, United States Planet Pharma Full time

    613284Our client, a leading Biotechnology company in Cambridge, MA , is looking for a Principal Scientist, Protein Production & Process Development with experience producing protein lead and Development Candidate molecules, preferably with both mammalian and E. coli production processes. The Principal Scientist will engage a diverse team of research...


  • Cambridge, United States Planet Pharma Full time

    613284Our client, a leading Biotechnology company in Cambridge, MA , is looking for a Principal Scientist, Protein Production & Process Development with experience producing protein lead and Development Candidate molecules, preferably with both mammalian and E. coli production processes. The Principal Scientist will engage a diverse team of research...


  • Cambridge, United States Planet Pharma Full time

    613284Our client, a leading Biotechnology company in Cambridge, MA , is looking for a Principal Scientist, Protein Production & Process Development with experience producing protein lead and Development Candidate molecules, preferably with both mammalian and E. coli production processes. The Principal Scientist will engage a diverse team of research...


  • Cambridge, Massachusetts, United States Novartis Group Companies Full time

    Job SummaryAs a Senior Principal Scientist in the Translational Medicine Drug Disposition Bioanalytical group at Novartis Group Companies, you will have the opportunity to make a significant impact in the development of novel modality biologics. This vital leadership role requires a collaborative nature, a commitment to teamwork, and a relentless focus on...


  • Cambridge, Massachusetts, United States Bristol-Myers Squibb Full time

    Transforming Patients' Lives through ScienceBristol-Myers Squibb is a leading biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines that transform patients' lives. We are seeking a highly skilled and experienced Senior Principal Scientist/Associate Director Neurology to join our Translational Medicine team.About...


  • Cambridge, Massachusetts, United States WilsonHCG Full time

    Job Summary:WilsonHCG is seeking a highly skilled Principal Scientist Nucleic Acid Medicine to join our team in the Cambridge area. As a key member of our Nucleic Acid team, you will be responsible for building a highly functional and collaborative team of Subject Matter Experts in the world of MRNA and LNP.About the Role:This is a great opportunity for...


  • Cambridge, Massachusetts, United States Generation Bio Full time

    Job Summary:Generation Bio is seeking a highly motivated and experienced molecular biologist to join our team as a Principal Scientist. The successful candidate will have a strong background in mammalian cellular trafficking and a deep understanding of nuclear pore complex structure and function.Key Responsibilities:Design and optimize nuclear translocation...

Principal Scientist, Immunopeptidomics

4 months ago


Cambridge, United States Johnson & Johnson Full time

Johnson and Johnson is recruiting for a **Principal Scientist, Immunopeptidomics & Proteomics **for our site located in Cambridge, MA.

**Primary responsibilities**:

- Manage a team of wet lab scientists enabling proteomic insights across a wide variety of programs and therapeutic modalities.
- Plan, oversee and perform wet lab proteomic activities for immunogenicity assessment, therapeutic optimization, and biomarker discovery.
- Collaborate with bioinformatics, biologics discovery, chemistry, and safety to drive experiments across the drug discovery portfolio.

**Qualifications**:
**Education**:

- A Doctorate or Master’s Degree in Analytical Chemistry, Biochemistry, Molecular Biology, Pharmacology, Immunology, or a related field is required

**Required**:

- A minimum 8 years experience in a laboratory setting
- Experience with liquid chromatography (Waters nanoAcquity or Thermo EASY-nLC or UltiMate 3000) and mass spectrometry (Thermo QE, Exploris, Eclipse, Lumos or Bruker timsTOF) instrumentation
- Experience processing and analyzing large scale global proteomic datasets
- Strong team, process, and project coordination with the ability to handle several projects at a time
- Excellent interpersonal skills working with diverse colleagues

**Preferred**:

- 4+ years experience in a drug discovery environment
- Experience planning and performing immunopeptidomic/proteogenomic (MHC class I or 2) experiments
- Proficiency with lab liquid handling automation (Beckman Biomek, Hamilton Microlab STAR, TECAN Fluent, or Dynamic Devices Lynx)
- Experience leading a team of scientists

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.