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Associate Scientist/Scientist, Protein Science

4 months ago


Framingham, United States Schrodinger, Inc. Full time

We're seeking an Associate Scientist/Scientist in Protein Science to join us in our mission to improve human health and quality of life through the development, distribution, and application of advanced computational methods

As a member of our Therapeutics Group, you'll contribute to our rapidly-expanding portfolio of drug discovery programs and collaborations. Our discovery and early clinical development team includes a cross-functional group of scientists and drug developers with experience working on all common target classes and therapeutic areas. You'll be supported by more than 100 software developers and engineers, as well as a large-scale computational infrastructure to apply our proprietary physics-based drug design and optimization platform. Ten of the programs we've worked on have progressed into preclinical development with four currently in clinical trials and one approved by the FDA.

Who will love this job:

* A curious, motivated, and growth-minded problem-solver with excellent communication and interpersonal skills
* A proactive learner who's interested in macromolecular architecture (proteins, antibodies, nucleic acids) and eager to learn the gene-to-structure pipeline
* A dedicated scientist who can apply molecular biology and cell culture skills to the design and execution of large-scale macromolecular production to enable multiple drug discovery projects

What you'll do:

* Carry out molecular biology experiments (i.e., PCR, cloning, plasmid amplification, and working with external vendors)
* Establish and execute small- and large-scale protein expression in E. coli, insect, and mammalian cells, and maintain eukaryotic cells for all users in the team
* Follow established protocols and carry out small- and large-scale protein purifications (affinity, ion exchange, and size exclusion chromatography)
* Quantify proteins, analyze purity, control quality, document work, and archive reagents
* Miscellaneous work related to protein chemistry

What you should have:

* Prior experience in molecular biology and protein expression/purification in an academic or industrial setting
* Bachelor's or Master's degree in biology, chemistry, or a related field

Pay and perks:

Schrödinger understands it's people that make a company great. Because of this, we're prepared to offer a competitive salary, equity-based compensation, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have regular catered meals in the office, a company culture that is relaxed but engaged, and over a month of paid vacation time. Our Office Management team also plans a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been included in Crain's New York Best Places to Work, BuiltIn's NYC Best Place to Work, and Newsweek's list of America's 100 Most Loved Workplaces.

Sound exciting? Apply today and join us

As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.