Computational Chemistry Leader
7 days ago
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
DICE Therapeutics, a wholly owned subsidiary of Eli Lilly & Co., is an organization within Lilly Research Labs, a small molecule drug discovery organization with responsibilities spanning from target identification to candidate selection for clinical studies. We are looking to grow our diverse team of scientists. The Computational Chemistry and Cheminformatics (C3) group in DICE is seeking a drug hunting expert with experience applying advanced computational technologies to real-world molecular design, who can operate across the computational and medicinal chemistry fields to make our drug discovery engine faster and more powerful.
Apply now to join our team as a Computational Chemist and drive innovation in drug discovery
Responsibilities
- Lead the computational chemistry team at DICE. Oversee the strategic implementation of computational methods for Medicinal Chemistry Projects, both established and new.
- Work to improve the computational skills of DICE scientists. Help build and implement a strategy to use computational tools in the medchem space. Mentor scientific staff and contribute to their scientific and career development.
- Implement generative design and other forward-looking approaches to the design of novel pharmaceuticals.
- Design complex molecules and predict their properties using ground-breaking technologies integrating structural, chemical and biological data.
- Contribute to the strategy and execution of small molecule drug discovery programs, working closely with cross-functional project teams in a matrix environment.
- Champion and promote the use of computational chemistry and cheminformatics methods to expedite the Design-Make-Test-Analyze discovery cycle.
- Innovate and implement new technologies to accelerate and improve small molecule design.
- Identify and assess emerging computational methodologies, including AI/ML, and contribute to the scientific development direction for the group.
- Ph.D. in Computational Chemistry, Computational Medicinal Chemistry or related field.
- 8-10+ years of experience.
- Familiarity with the fundamental concepts of organic chemistry, medicinal chemistry, and ADME.
- Forward-looking approach to drug discovery, with an eye toward closed-loop design.
- High-level proficiency in scripting or programming languages such as Python.
- Proficiency in programming computational workflows in Knime or equivalent.
- Extensive expertise with molecular design software tools.
- Strong oral and written communication skills, organizational and leadership capabilities.
- Ability to work in a Linux/Unix enterprise environment.
- Authorship on peer-reviewed publications and/or inventorship on patents/patent applications.
-
Computational Chemistry Leader
6 days ago
San Francisco, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Advisor - Computational Chemistry
2 months ago
San Francisco, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
San Francisco, United States Generalproximity Full timeGeneral Proximity is a seed-stage startup developing the next generation of induced-proximity medicines. Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges, which have remained unapproachable to other modalities for decades. We are seeking first-rate C omputational Chemists,...
-
San Francisco, United States Generalproximity Full timeGeneral Proximity is a seed-stage startup developing the next generation of induced-proximity medicines. Our OmniTAC drug discovery engine furnishes molecules that co-opt existing cellular machinery to overcome therapeutic challenges, which have remained unapproachable to other modalities for decades. We are seeking first-rate C omputational Chemists,...
-
Senior Computational Chemist
5 days ago
San Francisco, California, United States Generalproximity Full timeAbout General ProximityWe are a pioneering biotechnology company dedicated to developing innovative medicines that address some of the most pressing healthcare challenges. Our mission is to harness the power of induced-proximity technologies to create life-saving treatments for patients in need.Job SummaryWe are seeking an experienced Senior Computational...
-
Chief Chemistry Officer
2 weeks ago
San Francisco, California, United States Rezotx Full timeAbout RezotxRezotx is a pioneering biopharmaceutical organization dedicated to enhancing the efficacy of drug development. Our vision is to revolutionize the understanding of human diseases through a comprehensive, disease-agnostic network biology platform.Leadership TeamOur leadership comprises distinguished scientists and experienced biotech executives...
-
Director, Peptide Chemistry R&D Leader
5 days ago
San Francisco, California, United States Johnson Service Group Full timeJob DescriptionJohnson Service Group is seeking a highly skilled Director, Peptide Chemistry R&D to lead our Peptide Research Department. As a key member of our team, you will be responsible for overseeing peptide design, synthesis, and research projects, collaborating with global teams and clients, and driving innovative solutions in peptide drug...
-
Chief Chemistry Officer
2 weeks ago
San Francisco, California, United States Rezo Therapeutics Full timeAbout Rezo TherapeuticsRezo Therapeutics is an innovative biopharmaceutical organization dedicated to transforming the landscape of drug development. Our objective is to significantly enhance the success rates of therapeutic advancements by establishing a comprehensive, disease-agnostic network biology platform that will revolutionize our comprehension of...
-
Director, Computational Chemistry
4 weeks ago
San Diego, United States X4 Life Sciences Full timeAbout the Role:An innovative biotech company focused on addressing complex challenges in drug discovery is seeking an accomplished Director of Computational Drug Discovery. This leader will drive the development and application of advanced physics-based algorithms and machine learning techniques to overcome critical bottlenecks in drug design. The ideal...
-
Director, Computational Chemistry
4 weeks ago
San Diego, United States X4 Life Sciences Full timeAbout the Role:An innovative biotech company focused on addressing complex challenges in drug discovery is seeking an accomplished Director of Computational Drug Discovery. This leader will drive the development and application of advanced physics-based algorithms and machine learning techniques to overcome critical bottlenecks in drug design. The ideal...
-
San Francisco, United States KA Recruiting Inc. Full timeWe are seeking a highly skilled and experienced Medical Technologist Team Lead to join our team at KA Recruiting Inc.About the Role:The successful candidate will be responsible for leading a team of Medical Technologists in the Chemistry department, ensuring the highest standards of patient care and laboratory results.Key Responsibilities:Lead and manage a...
-
Chemistry Educator
3 days ago
San Francisco, California, United States KIPP Public Schools Northern California Full timeAbout the RoleWe are seeking a highly skilled and dedicated Chemistry Educator to join our team at KIPP Public Schools Northern California. As a Chemistry Educator, you will play a critical role in bringing to life the academic and cultural visions of our schools.Key ResponsibilitiesDevelop and implement daily lesson plans and long-term curriculum design to...
-
Director, Computational Chemistry
2 weeks ago
San Diego, United States X4 Life Sciences Full timeAbout the Role:An innovative biotech company focused on addressing complex challenges in drug discovery is seeking an accomplished Director of Computational Drug Discovery. This leader will drive the development and application of advanced physics-based algorithms and machine learning techniques to overcome critical bottlenecks in drug design. The ideal...
-
Director, Computational Chemistry
2 weeks ago
san diego, United States X4 Life Sciences Full timeAbout the Role:An innovative biotech company focused on addressing complex challenges in drug discovery is seeking an accomplished Director of Computational Drug Discovery. This leader will drive the development and application of advanced physics-based algorithms and machine learning techniques to overcome critical bottlenecks in drug design. The ideal...
-
Director, Computational Chemistry
2 weeks ago
San Diego, United States X4 Life Sciences Full timeAbout the Role:An innovative biotech company focused on addressing complex challenges in drug discovery is seeking an accomplished Director of Computational Drug Discovery. This leader will drive the development and application of advanced physics-based algorithms and machine learning techniques to overcome critical bottlenecks in drug design. The ideal...
-
Director, Computational Chemistry
1 week ago
san diego, United States X4 Life Sciences Full timeAbout the Role:An innovative biotech company focused on addressing complex challenges in drug discovery is seeking an accomplished Director of Computational Drug Discovery. This leader will drive the development and application of advanced physics-based algorithms and machine learning techniques to overcome critical bottlenecks in drug design. The ideal...
-
Medicinal Chemistry Research Specialist
2 weeks ago
South San Francisco, California, United States Septerna Inc. Full timePOSITION OVERVIEWWe are looking for a skilled medicinal chemist to enhance our chemistry initiatives for various drug discovery projects, collaborating within a multidisciplinary team. Your responsibilities will include the design of novel compounds, conducting synthesis in our in-house laboratories, partnering with Contract Research Organizations (CROs),...
-
South San Francisco, California, United States Cytokinetics Full timeAbout the RoleCytokinetics is a pioneering biopharmaceutical company dedicated to developing innovative treatments for debilitating diseases affecting cardiac muscle performance. As a leader in muscle biology and mechanics, we're committed to discovering and commercializing first-in-class muscle activators and next-in-class muscle inhibitors.Key...
-
Senior Scientist in Medicinal Chemistry
1 week ago
South San Francisco, California, United States Septerna Full timeAbout SepternaSepterna is a pioneering biotechnology firm dedicated to developing transformative therapies for patients. Our goal is to establish ourselves as the premier company in G protein-coupled receptor (GPCR)-focused drug discovery. Utilizing our innovative Native ComplexTM Platform, we replicate GPCRs with their authentic structure, function, and...
-
Medicinal Chemistry Research Scientist
1 week ago
South San Francisco, California, United States Septerna Full timeAbout SepternaSepterna is a pioneering biotechnology firm dedicated to developing transformative therapies for patients. Our goal is to establish ourselves as the premier organization focused on G protein-coupled receptor (GPCR) drug discovery. Utilizing our innovative Native ComplexTM Platform, we replicate GPCRs with their authentic structure, function,...
