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Science Associate II

3 months ago

Detroit, United States BioIVT Full time
Job DescriptionJob Description

SUMMARY

The SA-II is responsible for sample processing and quality control assessment of our dissociated cell, primary cell and cell line products. The Associate will be required to perform tissue dissociations and cell isolations from fresh tissue and biofluid specimens for both standard and custom processing requests. Other duties include analytical flow cytometry and flow data analysis, cell line and primary cell culture, and PBMC and BMMC isolation. Experience with aseptic technique/sterile cell culture is a must. Possesses the capacity and aptitude to manage small laboratory projects and quality control processes. Self-motivation, multi-tasking and great attention to detail are required to be successful in this role, in addition to good project management and communication skills. This position demands a flexible individual who thrives in a fast paced, high throughput environment. Job tasks will often require extended periods of time working under cold temperatures.

REQUIRED: This position will ensure compliance with Environmental Health and Safety (EHS) policies, State Departments of Health, Good Documentation Practices (GDP), Good Laboratory Practice (GLP), Good Manufacturing Practices (GMP), Good Clinical Practices (GCP), Good Laboratory Practice (GLP), Standard Operating Procedures (SOPs), EMEA and FDA Guidelines, general State and Country Regulations such as but not limited to (CLIA, CAP, USP, ISO 9001, USDA regulations, HTA license, DEA and State Controlled Substance programs) where site appropriate.

ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

  • Fresh human tissue dissociation and cell cryopreservation

  • Cell characterization by analytical flow cytometry and flow data analysis

  • Establishing, maintaining and expanding primary cell cultures

  • Isolation of PBMCs and BMMCs

  • Daily documentation, log completion and lab notebook usage for sample processing and cell culture activities

  • Knowledge of and adherence to ISO9001 and CAP requirements

  • Proper handling and quality control of biomaterials according to Standard Operating Procedures

  • Data entry, thorough specimen tracking and database upkeep

  • Perform general laboratory and equipment maintenance according to CAP and ISO 9001 standards

  • Knowledge of relevant laboratory software and equipment

  • Efficient processing of standard and custom order requests

  • Effectively interact with internal and external customers regarding order requests

  • Identify and resolve any potential issues that may arise during order fulfillment

  • Cross-train within adjacent departments as assigned

  • Maintain all department supply orders

  • Adherence to all OSHA/MiOSHA specimen processing and handling requirements

  • Manage small laboratory projects as assigned; primary focus on cost, timelines, and QC processes

  • Participate in on-call scheduled rotations for special projects

  • Identify and develop improvements in departmental processes

  • Provide support for inventory management projects

  • Effective time management skills to monitor workflow and long-term project/process improvements