RESEARCH SCIENTIST, WEISS LAB

2 weeks ago


Cambridge MA USA, United States Massachusetts Institute of Technology Full time
REQUIRED: Ph.D. in synthetic biology/biological engineering/related discipline; four years' synthetic biology, genetic circuit engineering, or related experience; comprehensive knowledge of imaging and quantification techniques, including flow cytometry and confocal and immunofluorescence imaging; ability to master cell biology techniques, including transient and stable transfection of mammalian cell lines, RNAi and miRNA gene knock-down, DNA cloning, sub-cloning, PCR, RT-PCR, qPCR, and generating protein expression vectors; and ability to work collaboratively and independently. PREFERRED: primary cell and cell line cell culture experience; success leading research teams and working with industry collaborators; strong leadership/managerial/mentoring and scientific communication skills; and a history of publishing in journals. Job #23808

This is a one-year position with the possibility of an extension based on the availability of funding.

Employment is contingent upon the completion of a satisfactory background check.

3/12/24

RESEARCH SCIENTIST 2, Biological Engineering-Synthetic Biology Center-Weiss Lab, to join an interdisciplinary research lab seeking to create integrated biological systems capable of autonomously performing tasks related to the activities of therapeutic agents for a variety of applications, including immunotherapy. Will participate in government- and corporate-sponsored research in mammalian synthetic biology, including genetically encoded therapies that perform cell type classification and conditionally administer appropriate therapeutic molecules. These mammalian genetic circuits will sense cell state, including miRNA levels, and implement multi-input logic regulating the expression of proinflammatory cytokines. Genetic circuits will be encoded on RNA replicons and distinguish between cell types such as lung cancer and T cells. Cell type identification will be based on determining an optimal combination of low and high miRNAs present or absent in the relevant cell types. Another level of control will be based on externally-administered small molecules that modulate the stability of regulatory RNA binding proteins. Will also engineer subgenomic promoters of RNA replicons for optimized tandem expression of constitutive and small molecule-regulated payloads in cancer and immune cells.

  • Cambridge, United States Massachusetts Institute of Technology Full time

    REQUIRED: Ph.D. in synthetic biology/biological engineering/related discipline; four years' synthetic biology, genetic circuit engineering, or related experience; comprehensive knowledge of imaging and quantification techniques, including flow cytometry and confocal and immunofluorescence imaging; ability to master cell biology techniques, including...


  • Cambridge, United States Massachusetts Institute of Technology Full time

    POSTDOCTORAL ASSOCIATE, MAMMALIAN SYNTHETIC BIOLOGY, Biological Engineering-Synthetic Biology Center-Weiss Lab, to join an interdisciplinary academic research lab seeking to create integrated biological systems capable of autonomously performing usef Biology, Doctor, Associate, Postdoctoral, Education


  • Cambridge, United States Massachusetts Institute of Technology Full time

    REQUIRED: Ph.D. in biological sciences, computer science, engineering, physics, math, or related field; experience in at least one of the following--mammalian cell culture, large-scale DNA assembly and characterization, genetic recombination technology, next-generation sequencing, computational methods and tools for analysis, and statistics; biological...

  • Research Scientist

    2 weeks ago


    Cambridge, United States Massachusetts Institute of Technology Full time

    Information on MITs COVID-19 vaccination requirement can be found at the bottom of this posting. RESEARCH SCIENTIST, Brain and Cognitive Sciences / Quest for Intelligence/ Computer Science and Artificial Intelligence Lab--Probabilistic Computing Pro Research Scientist, Research, Software Engineer, Scientist, Computer Science, Technology, Education, Program


  • Cambridge, United States Massachusetts Institute of Technology Full time

    RESEARCH SCIENTIST, PHYSIOLOGY, Mc. Govern Institute for Brain Research-Synthetic Neurobiology Group/ Boyden Lab, to join a lab that develops cutting-edge methods for imaging, mapping, and controlling the structure and function of the brain. Will rep Research Scientist, Research, Scientist, Neuro, Technology, Education

  • Research Scientist

    2 weeks ago


    Cambridge, United States Massachusetts Institute of Technology Full time

    REQUIRED: Ph.D. in computer science, mathematics, or related field or a master's and five years' experience, ideally through at least one postdoctoral appointment; ability to work effectively in a highly variable, dynamic, and unstructured environment across all levels with faculty, staff, students, and other MIT community members; and attention to detail....

  • Research Scientist I

    2 weeks ago


    Cambridge, United States Broad Institute Full time

    Description & Requirements The Sabeti Lab (, Harvard University, Broad Institute) and The Shalek Lab (, MIT, Broad Institute, and Ragon Institute) have a joint opening for a highly motivated Research Scientist I interested in studying host-pathogen interactions at a single-cell resolution. Research directions will center on interrogating the dynamic...


  • Cambridge, United States Massachusetts Institute of Technology Full time

    REQUIRED: bachelor's degree in a related field; two years' experience in laboratory research; experience with research grant writing and reporting processes; ability to understand the laboratory's work and express it verbally and in writing; knowledge of grant funding resources and experience coordinating applications; excellent organizational,...


  • Cambridge, United States Third Rock Ventures Full time

    Fulcrum Therapeutics is a clinical-stage biopharmaceutical company focused on improving the lives of patients with genetically defined rare diseases in areas of high unmet medical need. Fulcrum's two lead programs in clinical development are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystrophy (FSHD) and pociredir, a small...


  • Cambridge, United States Waters Corporation Full time

    Come and join our diverse research team in the heart of Cambridge and help us in this new era of innovation! Participate in collaborations across departments, sites and more broadly with the scientific and technical community world-wide. Waters Globa Research Scientist, Analytical, Research, Technical Support, Scientist, Chemistry, Manufacturing, Technology


  • Cambridge, United States Massachusetts Institute of Technology Full time

    RESEARCH SCIENTIST 3, Computer Science and Artificial Intelligence Laboratory (CSAIL) (part-time, 30%), to work with Dr. Neil Thompson as part of the Future. Tech research project. Will be responsible for working collaboratively on projects that unco Research Scientist, Research, Part-Time, Computer Science, Computer Scientist, Scientist, Technology,...


  • Cambridge, United States Massachusetts Institute of Technology Full time

    CLINICAL INVESTIGATOR/ RESEARCH SCIENTIST, Koch Institute for Integrative Cancer Research, to join the Charles W. (1955) and Jennifer C. Johnson Clinical Investigator program. This unique program is designed to create the next generation of physician Research Scientist, Clinical, Investigator, Research, Scientist, Technology, Education, IT


  • CAMBRIDGE, MA, United States Technology Recruiting Solutions Full time

    We have been engaged to find a Protein Engineering Scientist with hands-on experience in antibody/protein design and lab development with a focus on Yeast Surface Display projects. The position will work closely with experienced scientists in a dynamic, fast-paced and highly collaborative environment.In this role, you will play a key role in design and...


  • Cambridge, United States GForce Life Sciences Full time

    Associate ScientistDuration: 6-month contract Location: Cambridge, MADescription: We are looking for a highly motivated Associate Scientist to join our small molecule structural biology and biophysics efforts within our department of Biotherapeutic and Medicinal Sciences as a contract role for 6 months. The successful candidate will be a part of a fast-paced...


  • Cambridge, United States GForce Life Sciences Full time

    Associate ScientistDuration: 6-month contract Location: Cambridge, MADescription: We are looking for a highly motivated Associate Scientist to join our small molecule structural biology and biophysics efforts within our department of Biotherapeutic and Medicinal Sciences as a contract role for 6 months. The successful candidate will be a part of a fast-paced...


  • Cambridge, MA 02138, USA, United States Massachusetts Institute of Technology Full time

    REQUIRED: bachelor's degree in a specialized or related field based on hiring lab; at least two years of related lab experience; excellent organizational, communication, and interpersonal skills; attention to detail; proactive approach to responsibilities and consistent follow-through; and ability to prioritize and effectively manage time. Job #23660reposted...

  • Research Scientist

    2 weeks ago


    Cambridge, United States Waters Corporation Full time

    Come and join our diverse research team in the heart of Cambridge and help us in this new era of innovation! Participate in collaborations across departments, sites and more broadly with the scientific and technical community world-wide. Waters Globa Research Scientist, Instrument, Analytical, Research, Technical Support, Scientist, Manufacturing, Technology


  • Cambridge, United States Massachusetts Institute of Technology Full time

    REQUIRED: high school diploma or its equivalent; computer skills; training in hands-on equipment maintenance; practiced documentation skills; meticulous attention to detail; self-motivation; ability to exceed quality standards, provide exceptional services, and produce accurate and high-quality work; awareness of safe work practices and ability to follow...

  • Research Scientist

    7 days ago


    Cambridge, United States IBM Corporation Full time

    Introduction At IBM, work is more than a job - it's a calling: To build. To design. To code. To consult. To think along with clients and sell. To make markets. To invent. To collaborate. Not just to do something better, but to attempt things you've never thought possible. Are you ready to lead in this new era of technology and solve some of the world's most...


  • Cambridge, United States Massachusetts Institute of Technology Full time

    REQUIRED: Ph.D. or M.D.; clinical appointment in the greater Boston/Cambridge area in a cancer-related clinical specialty; demonstrated track record of scientific productivity; and a vision for independent research program in cancer biology, cancer-related biological engineering, or cancer therapeutics. Job #22547 Salary will be commensurate with level of...