Research Support Associate, Soto-Feliciano Lab

3 weeks ago


Cambridge, United States Massachusetts Institute of Technology Full time

REQUIRED: high school diploma or its equivalent; computer skills; training in hands-on equipment maintenance; practiced documentation skills; meticulous attention to detail; self-motivation; ability to exceed quality standards, provide exceptional services, and produce accurate and high-quality work; awareness of safe work practices and ability to follow safety procedures and maintain a safe work environment; willingness to work with animals; excellent oral and written communication skills; and ability to work on teams in a fast-paced environment. PREFERRED: B.S. in biology/chemistry/STEM field; exposure to a research lab; and experience with cell culture, molecular biology, and/or biochemical techniques. Job #23001-3

This is a two-year, term position with the possibility of an extension.

7/26/23

RESEARCH SUPPORT ASSOCIATE, Koch Institute for Integrative Cancer Research-Soto-Feliciano Lab, to contribute to independent research projects--run by postdoctoral and doctoral scientists--that are focused on epigenetic mechanisms of normal development and cancer. Research techniques will include mammalian cell culture; basic molecular biology techniques (PCR and molecular cloning, protein analyses); standard chromatin assays (ChIP and related methods); next-gen sequencing (library preparation and basic analyses); and confocal microscopy, including sample preparation, imaging, and analyses. Other duties include maintaining stocks of reagents and cell lines and occasional work with vertebrate animals (mice).

The Soto-Feliciano Lab is interested in understanding how chromatin adaptor proteins help decode the chemical language of chromatin (the physiological form of our genomes), their context-specific effects, and how they regulate gene expression in normal physiology and disease. These studies will improve our basic understanding of how protein complexes assemble on chromatin in a concerted and regulated manner, ultimately giving insight into the etiology of cancer and other human diseases and paving the way for therapeutic approaches that revert chromatin and epigenetic dysregulation.



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