Senior Principal Lab Technician
2 days ago
We are hiring Senior Principal Lab Technician Role.
Our Major Pharmaceutical Manufacturing Client is looking for Senior Principal Lab Technician in Cambridge, MA 02139 for 6+ months contract.
Please let me know if you are interested or anyone who might be interested.
Job Details:
Client: Major Pharmaceutical Manufacturing Client
Duration: 6+ months
Location: Cambridge, MA 02139
Title: Senior Principal Lab Technician
Pay Rate: $32.00 - $34.00/ Hr W2
Education: BS, MS, or PhD in relevant scientific field
Experience: If BS, then 11+ years. If MS, then 9+ years. If PhD, then 2-3 years of previous work experience.
Minimum 3 years of industry experience of hands-on NGS library generation and operating Illumina sequencing platform is required
Description:
• Establish workflows utilizing next-generation sequencing technologies to advance antibody discovery efforts from in vitro (yeast and phage), in vivo (single/bulk B cells) or de novo (AI based) platforms with the goal to more deeply interrogate repertoires, expand our knowledge of functional and sequence diversity and accelerate lead discovery.
• Working with computational scientists, establish data analysis pipelines for NGS data.
• Investigate use of NGS in other areas in Global Biologics to accelerate workflows and to enhance pipeline support and accelerate programs to IND.
• Develop and optimize NGS protocols for library generation, sequencing using Illumina MiSeq/NextSeq platforms, and library QC and analysis.
• Establish workflows using NGS in other areas in Global Biologics including cell line generation, plasmid preparation and CAR-T design characterization.
• Generate high quality NGS library (e.g. RNASeq, CITE-Seq) by rigorous optimization and QC process.
• Ability to perform DNA library fragment purification using Blue Pippin and analyze the size using Tape Station 4200.
• Library quantification using qubit and qPCR.
• Continuously improve NGS workflows with integration of automation and informatics.
• Deeply understand and troubleshoot NGS experiments to ensure assay robustness and generation of high-quality data.
• Meet established timelines, maintain accurate records of work.
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