Head of Preclinical Development

1 month ago

Cambridge, United States Third Rock Ventures Full time

A well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking an experienced Head of of Preclinical Development. Reporting to the CSO, the Head of Preclinical Development will play a wide-ranging role in helping to develop a mature pipeline of drug candidates for the company. This role will be responsible for integrating key functional workstreams required for the preclinical development of biotherapeutics including pharmacology, toxicology, and bioanalytics. The ideal candidate will have 15+ years of experience in the Biotech/Pharmaceutical industry, have filed multiple INDs, and be a recognized leader in Pharmacology, Toxicology or Bioanalytics.


Responsibilities

  • Using an approach grounded in objectivity and scientific rigor, oversee all internal and external preclinical development activities
  • Working within a matrix team ensure the development and execution of preclinical development activities including pharmacology, toxicology, and bioanalytics
  • Provide leadership, strategic oversight, resource management, and organizational framework to ensure timely decision making on projects
  • Identify, support, manage and develop talent among team; act as a resource and mentor to team members by providing guidance, instruction, feedback and ongoing coaching; encourage visionary thinking. Value the advancement of our programs and our people. Preserve and promote current model of participative decision making in an organization where siloes are nonexistent and discouraged
  • Contribute to the integration of Discovery Research, CMC and clinical organizations
  • Professionally represent the organization externally in collaborations and conferences, board of directors and scientific advisory board meetings

About You

  • Ph.D. in Pharmacology, Immunology or related field
  • 15+ years of pharmaceutical/biotech industry experience and a minimum of 8 years in one of the key predevelopment domains listed above
  • Experience working directly with Drug Discovery, Safety Assessment, Regulatory, Technical Operations & Clinical Development
  • Extensive knowledge of biotherapeutic research and development and thorough understanding of the tasks and deliverables required to mature assets through preclinical development, IND filing and drug development.
  • A strong understanding of the people, processes and infrastructure involved in managing across the drug development lifecycle.
  • Ability to prioritize and execute multiple tasks with a strong attention to detail in a high-intensity, high-visibility environment.
  • Strong communication and ability to influence across all levels of the organization, including executive leadership
  • Strong analytical capabilities, including quantitative and qualitative assessment skills and demonstrated critical thinking skills
  • Ability to distill complex issues and ideas into simple, comprehensible terms
  • Strong leadership, mentoring and team building skills
  • Passion for making a difference in the world through the creation of new medicines

  • Head of Preclinical Development

    7 hours ago

    cambridge, United States Third Rock Ventures Full time

    A well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking an experienced Head of of Preclinical Development. Reporting to the CSO, the Head of Preclinical Development will play a wide-ranging role in helping to develop a mature pipeline of drug candidates for the...

  • Head of Preclinical Development

    1 month ago

    Cambridge, United States Third Rock Ventures Full time

    A well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking an experienced Head of of Preclinical Development. Reporting to the CSO, the Head of Preclinical Development will play a wide-ranging role in helping to develop a mature pipeline of drug candidates for the...

  • Head of Development, Ex Vivo Programs

    4 weeks ago

    Cambridge, Massachusetts, United States Intellia Full time

    How you will Achieve More with Intellia:We are hiring a Head of Development for Ex Vivo Programs to oversee all functions for the ex vivo programs, including clinical, regulatory, and biometrics.You will act as a Program Team Lead for an innovative new Ex Vivo Cell Therapy Program.You will be responsible for the development and execution of short and...

  • Head of Development, Ex Vivo Programs

    3 weeks ago

    Cambridge, United States Intellia Full time

    How you will Achieve More with Intellia:We are hiring a Head of Development for Ex Vivo Programs to oversee all functions for the ex vivo programs, including clinical, regulatory, and biometrics.You will act as a Program Team Lead for an innovative new Ex Vivo Cell Therapy Program.You will be responsible for the development and execution of short and...

  • Principal Immunologist, Preclinical Research

    2 days ago

    Cambridge, Massachusetts, United States Flagship Ventures Full time

    Job SummaryWe are seeking a highly skilled PhD-level Principal Scientist with expertise in immunology and preclinical research to join our team at Flagship Ventures.Key ResponsibilitiesLead and manage immunology and preclinical research projects, ensuring scientific rigor and excellence.Develop and validate immunological assays (e.g., flow cytometry, ELISA,...

  • Director, Preclinical Drug Safety

    2 weeks ago

    Cambridge, United States Blueprint Medicines Full time

    How will your role help us transform hope into reality? Reporting to the Vice President of Preclinical Drug Safety, you will be responsible for developing and implementing toxicology strategies for multi-disciplinary program teams. You will play a critical role helping derisk and advance the research pipeline by leveraging your toxicology expertise,...

  • Director, Preclinical Drug Safety

    2 days ago

    Cambridge, United States Blueprint Medicines Full time

    How will your role help us transform hope into reality?Scroll down the page to see all associated job requirements, and any responsibilities successful candidates can expect.Reporting to the Vice President of Preclinical Drug Safety, you will be responsible for developing and implementing toxicology strategies for multi-disciplinary program teams. You will...

  • Associate Scientist

    4 weeks ago

    Cambridge, United States Simcere Of America Inc Full time

    Simcere is expanding its Boston Innovation Center with a dynamic drug discovery team based in Cambridge, Massachusetts. We are on the lookout for innovative, driven, and autonomous Associate Scientist to enhance our preclinical research division. This role presents an exciting chance to leverage your scientific knowledge in pioneering experiments designed to...

  • Associate Scientist

    1 month ago

    Cambridge, United States SIMCERE OF AMERICA, INC Full time

    Simcere is expanding its Boston Innovation Center with a dynamic drug discovery team based in Cambridge, Massachusetts. We are on the lookout for innovative, driven, and autonomous Associate Scientist to enhance our preclinical research division. This role presents an exciting chance to leverage your scientific knowledge in pioneering experiments designed to...

  • Associate Scientist

    5 days ago

    cambridge, United States SIMCERE OF AMERICA, INC Full time

    Simcere is expanding its Boston Innovation Center with a dynamic drug discovery team based in Cambridge, Massachusetts. We are on the lookout for innovative, driven, and autonomous Associate Scientist to enhance our preclinical research division. This role presents an exciting chance to leverage your scientific knowledge in pioneering experiments designed to...

  • Associate Scientist

    5 days ago

    cambridge, United States SIMCERE OF AMERICA, INC Full time

    Simcere is expanding its Boston Innovation Center with a dynamic drug discovery team based in Cambridge, Massachusetts. We are on the lookout for innovative, driven, and autonomous Associate Scientist to enhance our preclinical research division. This role presents an exciting chance to leverage your scientific knowledge in pioneering experiments designed to...

  • Associate Scientist

    1 month ago

    Cambridge, United States SIMCERE OF AMERICA, INC Full time

    Simcere is expanding its Boston Innovation Center with a dynamic drug discovery team based in Cambridge, Massachusetts. We are on the lookout for innovative, driven, and autonomous Associate Scientist to enhance our preclinical research division. This role presents an exciting chance to leverage your scientific knowledge in pioneering experiments designed to...

  • Director, Preclinical Drug Safety

    2 weeks ago

    Cambridge, United States Blueprint Medicines Full time

    How will your role help us transform hope into reality?Do you have the right skills and experience for this role Read on to find out, and make your application.Reporting to the Vice President of Preclinical Drug Safety, you will be responsible for developing and implementing toxicology strategies for multi-disciplinary program teams. You will play a critical...

  • Scientist in Preclinical Pharmacology

    5 days ago

    Cambridge, Massachusetts, United States Vaxess Technologies Full time

    Location: Cambridge, MAVaxess Technologies is at the forefront of developing advanced vaccines and therapies utilizing its proprietary MIMIXTM Microneedle Array Patch technology. This innovative approach allows for self-administration of vaccines and therapeutics to the skin, potentially enhancing shelf-stability, tolerability, and overall efficacy. Our...

  • Head of Development, Ex Vivo Programs

    3 months ago

    Cambridge, Massachusetts, United States Intellia Therapeutics Full time

    Why Join Intellia?Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to...

  • Head of Development, Ex Vivo Programs

    3 months ago

    Cambridge, United States Intellia Therapeutics Full time

    Why Join Intellia?Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to...

  • Head of Development, Ex Vivo Programs

    3 months ago

    Cambridge, United States Intellia Therapeutics Full time

    Why Join Intellia? Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.   Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded...

  • Head of Analytical Development

    5 days ago

    Cambridge, Massachusetts, United States Takeda Full time

    About the RoleWe are seeking a highly experienced and skilled professional to lead our Analytical Development team as the Head of Analytical Development. This is a critical role that requires a strong background in pharmaceutical sciences, quality assurance, and regulatory compliance.Key ResponsibilitiesLead and develop a global team of managers and...

  • Associate Director, Program Management, Research

    3 months ago

    Cambridge, United States Moderna, Inc. Full time

    The Role:Moderna is seeking a highly motivated and experienced Associate Director to lead and oversee program managers within our research and preclinical stage programs. This role will involve strategic oversight and coordination of multiple programs, ensuring alignment with corporate objectives and milestones. The successful candidate will be pivotal in...

  • Manager - Business Development

    2 months ago

    Cambridge, Massachusetts, United States Novo Nordisk Full time

    About the Department The Novo Nordisk Cambridge location is the headquarters for Global Business Development across all of our therapeutic and technology areas. We contribute to innovation in one of the world's largest life sciences ecosystems by participating in events and discussions with renowned and upcoming scientists looking for the next scientific...