Scientist I

1 month ago


Lexington, Kentucky, United States Novo Nordisk Full time

About the Department

Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown, Cambridge and Seattle reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.

The Position

The Scientist will provide technical leadership in complex in vitro and in vivo workflows, identification and validation of new drug targets, advancing novel therapies, and developing technologies to accelerate scientific research. This will be achieved by coordinating multiple research activities involving cross-functional project teams to ensure achievement of key deliverables. The Scientist will represent the organization to the external scientific community through publication and presentation of research, and through the development, management, and leadership of external collaborations. The individual will be seen across the company as a method/subject expert for one or two technologies or area(s) of biology.

Relationships

This is a full-time position in the Obesity, Diabetes and MASH Therapeutic Area at Novo Nordisk located in Lexington, MA, USA.

Internal relationships include working closely with technical staff & other members of the scientific leadership team; regular collaborations with members of other research departments in Boston; & frequent interaction with project managers & other colleagues in Denmark, Oxford and Beijing. Individual may be responsible for indirect reports or contingent workers.

Individual will interact with external research collaborators, both academia- & industry-based.

Essential Functions

Design and perform in vitro and in vivo experiments for target ID, validation and MoA in the area of obesity and diabetes. Evaluate novel biology, methodologies, and implement new assays and platforms for target validation and investigation of pharmacological MoA.Support and drive drug discovery projects (target, biology, or technology-related)Generate new target ideas/hypotheses and propose experiments to mature the idea and validate the hypotheses for decision makingAnalyze and interpret complex data, drive conclusions, and next step. Present data and recommendation for next steps to cross-functional project teams.Evaluate novel biology, methodologies, and implement new assays and platforms for target validation and investigation of pharmacological MoA.Author internal reports, protocols, patents, external publications in peer-reviewed journals and presentations at external scientific conferencesMaintain a strong understanding of theoretical knowledge and a connection to the external scientific community through continuous evaluation of relevant literature.Experience with in silico analyses and large datasets is highly desired.Author internal reports, protocols, and external publications.Effectively communicates and collaborates across global sites and guides project strategy by providing expert input to cross-functional project teams.Represent the organization at scientific conferences and global meetings by authorship and publication of scientific papers and patents.Maintain a strong understanding of theoretical knowledge and a connection to the external scientific community through continuous evaluation of relevant literature.Leads cross-functional experimental teams to achieve project goals, mentor junior staff, and provide trainingInfluences the research pipeline by recommending, presenting, and championing new targets or methodologies.Works with Department Heads and Scientists to ensure better practice sharing and implementation within the research environment. QualificationsPhD degree with a minimum of 2 years postdoctoral and/or industry experience in neural regulation of hunger and satiety Has hands on experience with in vitro neuronal culture, ex vivo and in vivo techniques to study neural regulation of appetite and energy expenditure Has expertise and in-depth knowledge in neurocircuitry and metabolism Demonstrated productivity and relevant expertise/experience in his/her scientific publicationsHas excellent verbal and written communication skills.Experience with in silico analyses and large datasets is a plus. Collaborative and a team player Open to hiring at a higher level commesurate with experience We commit to an inclusive recruitment process and equality of opportunity for all our job applicants. At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we're life changing. Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations. If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at This contact is for accommodation requests only and cannot be used to inquire about the status of applications.
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