Research Associate II

4 weeks ago


South San Francisco, California, United States ICONMA Full time

The Antibody Engineering Department at Genentech works to shape the future of medicine by discovering life-changing antibody therapies through pioneering science.We are seeking a dedicated and independent Scientist 2/3 with strong molecular biology skills and experience in the design and assembly of antibody encoding plasmids for expression from mammalian cellsThis is a hands-on, lab-based position that requires close collaboration with colleagues in the Antibody Engineering and is in support of various projects across multiple functions in Genentech Research.Apply molecular biology skills to drive the rapid assembly of antibody encoding plasmids for expression from mammalian cells.Interact with informatic engineers to develop processes that support automated antibody development workflows including antibody (DNA and protein sequence) registration, tracking, archiving, and inventory.The successful candidate will have a B.S. or M.S. degree in molecular biology or related science and 4+ years of applying molecular biology skills, preferably in an antibody research or industrial setting.Experience and expertise in performing polymerase chain reactions (PCR), general DNA plasmid construct assembly, steps necessary for antibody clone isolation including bacterial transformation, bacterial colony picking, bacterial clone culturing, plasmid purification at the mini to maxi scale, and analyzing DNA sequences.Basic molecular biology skills in DNA ligation, DNA mutagenesis, oligonucleotide design, and endonuclease restriction digestion analysis are also required.


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