Current jobs related to Senior Scientist I/II, Computational Biology - Cambridge, Massachusetts - Sail Biomedicines
-
Senior Scientist, Biology Lead
1 week ago
Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full timeAbout the OpportunityCrossbow Therapeutics, Inc. is a biotechnology company dedicated to revolutionizing cancer treatment through innovative immunotherapies. We are seeking a highly skilled Senior Scientist/Principal Scientist, Biology to join our dynamic team.Key Responsibilities:Lead programs from discovery through DC nomination, driving scientific rigor...
-
Senior/Principal Scientist, Biology
1 week ago
Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full timeCrossbow Therapeutics, Inc. is a biotechnology company dedicated to improving the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. Our T-BoltTM therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell targets. Our approach...
-
Senior Scientist, PSC Biology
2 weeks ago
Cambridge, Massachusetts, United States BlueRock Therapeutics Full timeJob Title: Senior Scientist, PSC BiologyJob Summary:BlueRock Therapeutics is seeking a highly skilled Senior Scientist, PSC Biology to lead the development, testing, and implementation of novel NGS sequencing technologies to characterize human pluripotent stem cells (hPSCs) and their differentiated progeny at the molecular, (epi-) genomic level.Key...
-
Senior/Principal Scientist, Biology
4 weeks ago
Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full timeAbout the OpportunityCrossbow Therapeutics, Inc. is a biotechnology company dedicated to improving the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. Our T-BoltTM therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell...
-
Senior Scientist II/III, Biological Sciences
3 weeks ago
Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full timeJob OpportunityWe are seeking a highly motivated and self-driven individual to join our Biological Sciences oncology drug discovery group as a Senior Scientist II/III. This role requires working closely with a multidisciplinary research team to discover new small molecule therapeutics for the treatment of cancer.The successful candidate will work...
-
Computational Biology Research Leader
4 weeks ago
Cambridge, Massachusetts, United States Broad Institute Full timeJob Title: Group Leader, Computational Biology, Xavier LabAbout the Role:We are seeking a highly motivated and experienced Group Leader in Computational Biology to lead and direct investigations into the mechanisms of host microbiome interactions in health and disease. As a key member of our interdisciplinary team, you will work closely with computational...
-
Computational Biology Group Leader Position
2 weeks ago
Cambridge, Massachusetts, United States Broad Institute Full timeJob Title:Group Leader, Computational BiologyJob Summary:We are seeking a highly experienced and motivated Group Leader in Computational Biology to lead our research efforts in understanding host microbiome interactions in health and disease.Responsibilities:Design and execute collaborative studies to investigate host microbiome interactionsDevelop and...
-
Data Scientist, Computational Biology
4 weeks ago
Cambridge, Massachusetts, United States Repertoire Immune Medicines Full timeJob DescriptionRepertoire Immune Medicines is a biotechnology company dedicated to unlocking the potential of the human immune system to treat cancer and autoimmune diseases. Our team is working to develop novel targeted immune medicines using the DECODE platform, which enables in-depth characterization of TCR-antigen pairs. We are seeking a talented Data...
-
Research Scientist II
1 month ago
Cambridge, Massachusetts, United States Repertoire Immune Medicines Full timeJob Title: Research Associate II/Senior Research AssociateJob SummaryRepertoire Immune Medicines is seeking a highly motivated Research Associate II/Senior Research Associate to join the Applied Immunology team. This team is responsible for innovation and early development of Repertoire's immunotherapeutics. The successful candidate will support a team of...
-
Postdoctoral Researcher in Computational Biology
3 weeks ago
Cambridge, Massachusetts, United States The University of Texas MD Anderson Cancer Center Full timePostdoctoral Position in Computational BiologyWe are seeking a highly motivated postdoctoral researcher to join our team in the Carpenter-Singh laboratory at the Broad Institute of Harvard and MIT. The successful candidate will have a strong background in computational biology and a passion for developing novel methods to extract quantitative information...
-
Research Scientist I
2 weeks ago
Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full timeResearch Scientist I, Biology-Vos LabWe are seeking a highly motivated Research Scientist I to join our research team studying the intricate relationship between gene expression and genome architecture.The successful candidate will lead an individual project and collaborate with a larger team to investigate how gene expression and genome organization...
-
Scientist I
2 weeks ago
Cambridge, Massachusetts, United States US Tech Solutions Full timeJob Title: Scientist IWe are seeking a highly motivated and passionate scientist in cellular immunology to join our team in Immunology Discovery department based in Cambridge, MA.The successful candidate will focus on making therapeutic molecules using recombinant DNA technology, expression/purification of recombinant proteins, testing purified proteins in...
-
Senior/Principal Scientist, Biology
4 days ago
Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full timeCrossbow Therapeutics, Inc. is a biotechnology company dedicated to improving the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies.The company's T-BoltTM therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell targets. Our...
-
Cambridge, Massachusetts, United States Biogen Full timeOur team in Computational Biology at Biogen is seeking a Co-op Data Scientist to join our team for a 6-month student role from January to June 2025.The aim of our team is to perform high-quality computational analysis on genomics/transcriptomics datasets, standardize NGS data analysis pipelines, and work on cutting-edge AI/ML tools and technologies.Key...
-
Senior Scientist, Disease Area Biology
4 weeks ago
Cambridge, Massachusetts, United States Korro Bio, Inc. Full timeJob Summary:Korro Bio, Inc. is seeking a highly motivated and experienced Senior Scientist to join our Disease Area Biology team. As a key member of our team, you will contribute to and lead drug discovery efforts for brain and spinal cord disorders. The successful candidate will design and conduct experiments in human cell lines to advance discovery...
-
Senior Scientist, II
4 days ago
Cambridge, Massachusetts, United States AbbVie Full timeJob OpportunityWe are seeking a highly motivated and talented Senior Scientist II to join our Molecular Profiling and Drug Delivery (MPDD) function within the Small Molecule CMC organization.About the RoleThis role will serve as an MPDD project leader on discovery programs, leading CMC developability assessment for emerging molecules on small molecule...
-
Cambridge, Massachusetts, United States Flagship Pioneering Full timeAbout the Role:We are seeking a highly skilled Senior Research Scientist to join our team at Flagship Pioneering. As a Senior Research Scientist, you will be responsible for developing and applying computational skills to understand complex biological systems and their relationship to clinical state changes.Key Responsibilities:Design and implement novel...
-
Senior Bioinformatics Scientist
1 week ago
Cambridge, Massachusetts, United States Flagship Ventures Full timeUnlock the Power of Computational BiologyWe are seeking a highly skilled Senior Bioinformatics Scientist to join our Pioneering Medicines Translational Sciences Team. As a key member of our team, you will lead the computational efforts on drug discovery programs, integrating, analyzing, and interpreting omics data to drive target discovery, translational,...
-
Cambridge, Massachusetts, United States Flagship Pioneering Full timeCompany Overview:Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. With a proven track record of success, Flagship has originated and fostered over 100 scientific ventures, resulting in over $90 billion in aggregate...
-
Cambridge, Massachusetts, United States Flagship Pioneering Full timeCompany Overview:Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Our mission is to leverage advanced biological and computational platforms to discover breakthroughs in detection of and intervention against the...
Senior Scientist I/II, Computational Biology
3 months ago
About Sail:
Sail Biomedicines is harnessing evolutionary and artificial intelligence to revolutionize programmable medicines. Sail's platform combines first-in-class programmable RNA technology (Endless RNATM or eRNA), and an industry-leading platform of programmable nanoparticles, utilizing natural components, to unlock comprehensive programming of medicines for the first time. By leveraging cutting-edge eRNA and nanoparticle deployment technology, Sail is building a wealth of data, enabling unparalleled use of AI techniques to identify and design fully programmable medicines that are potent, targeted, versatile, and tunable. Sail was founded by Flagship Pioneering.
The Role:
The Sail Biomedicines Data Science team is looking for a talented Computational Biologist seeking an environment where they can make an impact. As a key member of the Sail Data Science Team, the Senior Scientist II will lead efforts in a cross-disciplinary team of experimental, computational, and machine learning scientists and engineers to drive the development and extension of Sail's AI-driven programmable medicine platform, thereby pushing a new class of RNA-medicines towards the clinic.
Responsibilities:
Strategic Pipeline Development and Optimization: Oversee the design, implementation, and continuous enhancement of advanced, scalable computational pipelines for a range of high throughput sequencing data types (e.g., RNA-Seq, Amplicon-Seq, scRNA-Seq) and other large-scale biological data. Innovate and drive improvements in pipeline architecture to meet evolving research demands and industry trends. Comprehensive Documentation and Knowledge Sharing: Develop and manage detailed documentation integrated with our digital data backbone for pipeline workflows, analytical methods, and results. Ensure that documentation promotes reproducibility, transparency, and effective knowledge transfer across scientific and technical teams. Excellence in Quality Assurance: Lead the development and enforcement of rigorous quality control measures to ensure superior data accuracy, integrity, and reliability. Address and resolve complex issues related to data quality, pipeline performance, and system robustness with a strategic approach. Enterprise Data Management: Facilitate structured data capture, management, and integration at an enterprise level. Enhance data accessibility, utility, and governance across diverse scientific and research platforms. Advanced Data Analysis and Interpretation: Direct data analysis using advanced statistical and computational methods to evaluate and derive actionable insights from complex datasets across various scientific disciplines. Guide the interpretation and application of results, ensuring relevance to experimental methodologies and biological contexts, and inform strategic decision-making. Cross-Disciplinary Collaboration: Build and maintain strategic partnerships with multidisciplinary teams, including but not limited to computational biology, bioinformatics, genomics, systems biology, and data science. Drive the advancement of research programs and technology platforms from development through clinical and commercial applications. Communicate complex concepts effectively to diverse audiences. Project and Timeline Management: Supervise and manage multiple high-impact projects, ensuring alignment with strategic goals, adherence to timelines, and delivery of results. Provide guidance and oversight to ensure project success and timely completion.Qualifications:
PhD in Computational Biology, Bioinformatics, Computer Science, Statistics, Physics, or related field, with industry experience (4+ years), preferably in leadership roles with a track record of collaborating with various scientific disciplines. Expertise in Advanced Programming and Computational Tools: Proficiency in relevant programming languages (e.g., Python, R), advanced statistical analysis tools, and command line tools for NGS analysis. Proven ability to develop and optimize sophisticated computational solutions across diverse data types. Extensive Experience with Modern Technologies: Over 5 years of experience with version control systems (e.g., Git), reproducible computing (e.g., Docker), workflow management systems (e.g., Nextflow, Snakemake), and cloud computing platforms (e.g., AWS) or HPC environments. Proven Leadership in Computational and Analytical Projects: Demonstrated success in leading large-scale computational and analytical projects within multidisciplinary teams, with experience in mentoring and developing junior staff. Advanced Data Analysis Across Scientific Disciplines: Extensive experience in analyzing complex datasets from genomics, transcriptomics, proteomics, lipidomics, and other multi-omics fields. Skilled in applying advanced statistical and computational methods. Strategic Data Exploration: Evaluate datasets with strategic and innovative approaches and leverage data to enhance core informatics workflows and drive research and operational excellence. Exceptional Communication and Advocacy Skills: Strong ability to articulate complex methodologies and analyses to audiences with varying levels of technical expertise. Advocate for and implement digital-first and data-driven strategies across the organization. Innovation and Methodology Development: Proven ability to develop new methodologies, tools, and visualizations, with a focus on advancing research capabilities and operational efficiency.Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law.
