Senior Research Associate, Translational Sciences

1 month ago

Boston, Massachusetts, United States Entrada Therapeutics Full time
The Organization

What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible.

Our Endosomal Escape Vehicle (EEVTM)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA-, antibody- and enzyme-based programs for the potential treatment of neuromuscular, ocular, metabolic and immunological diseases, among others.

Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45 and 50 skipping amenable. We have also partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.

We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.The Perfect Addition to Our Team

You are self-motivated, highly collaborative, and eager to roll up your sleeves, as you will contribute to several aspects of our translational biology group. Your background should be in biology or biomedical engineering, with experience in cell biology, in vitro 2D and 3D disease models, and molecular biology. You will work alongside team members to help characterize and validate innovative medicines to treat some of the most challenging diseases.
The Opportunity

The Senior Research Associate will have the opportunity to work with disease models and cell-based assays, such as ddPCR, ELISA, LabChip, and confocal microscopy. They will support pre-IND and IND-enabling studies using in vitro cell systems. The ideal candidate will be managing and ordering chemicals and supplies, as well as preparing procedures and other reports. There will also be opportunities to present data and research findings at internal meetings.
Responsibilities
Maintain and culture the in vitro 2D and 3D cell models to support the in vitro preclinical studies.
Conduct experiments to critically assess in vitro assays (e.g. DNA/RNA/protein extraction, RT-PCR, RT-qPCR, ddPCR, western blot, ELISA, immunostaining, imaging, etc.) and data analysis.
Collaborate with Neuromuscular, Ocular, and Biologics groups for method transfer and to acquire materials for subsequent cell-based assay development and testing.
Ensure reagents for in vitro assay experiments are well stocked and keep a detailed record of all experiments in a digital lab notebook.
Present updates regularly in the translational group meetings.

The Necessities
At Entrada, our passion for science, our devotion to patients and our values drives our behavior:
Humanity - We genuinely care about patients and about one another.
Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
Creativity - We are creative problem solvers.
Collaboration - We are more than the sum of our parts.
Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

BS in biology, biomedical engineering, or a related field with 4+ years of industry experience (or a MS in related field with 2+ years' experience).
Strong communication and organizational skills.
Hands-on experience with in vitro assays including PCR, ddPCR, qPCR, Western blotting, and immunostaining.
Hands-on experience with muscle cells, organoid systems, and/or engineered tissues is a plus.
The ability to critically assess experimental results, troubleshoot, and come up with creative and effective solutions.
The drive to have a more complete understanding of project goals to effectively manage your time and prioritize experiments.
The Perks
By becoming a team member here at Entrada, you'll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you'll benefit from discretionary time off, paternity leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer.
Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.
Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.
Privacy Statement

Entrada Therapeutics, Inc. (the "Entrada," "we," "us," or "our") respects your privacy and we want you to be familiar with how we collect, use, share, or otherwise process, your Personal Information. Please reference our privacy statement here to understand how and when your data is being used.

  • Translational Science Protocol Coordinator

    7 days ago

    Boston, Massachusetts, United States Joulé Full time

    Job Title: Translational Science Protocol CoordinatorLocation: Remote/HybridHours/Schedule: Standard Business HoursType: Direct HireOverview We are seeking a dedicated professional to join our team. The ideal candidate will have substantial experience in oncology research, ideally around five years, though candidates with two to three years of relevant...

  • Senior Quantitative Researcher

    2 days ago

    Boston, Massachusetts, United States FactSet Research Systems Inc. Full time

    About the RoleWe are seeking a highly skilled and experienced Associate Director to join our Fixed Income Research and Development team at FactSet Research Systems Inc. This is a unique opportunity to lead a team of researchers and contribute to the development of advanced quantitative models and concepts for fixed income analytics.Key ResponsibilitiesLead a...

  • Associate Chief of Research- Division of Geographic Medicine

    4 weeks ago

    Boston, Massachusetts, United States Tufts Medicine Full time

    We're saving lives, building careers, and reimagining healthcare. We can't wait to grow alongside you. The Division of Geographic Medicine and Infectious Diseases at Tufts Medical Center in Boston is seeking a full-timeacademic Infectious Diseases specialistwith significant experience in clinical and/or translational research to lead the Divisional research...

  • Investigators at All Career Levels

    2 months ago

    Boston, Massachusetts, United States Tufts Medical Center, Research Full time

    Tufts University School of Medicine (TUSM) and Tufts Medical Center (TMC) are increasing joint research looking, to further develop exciting, forward-looking multidisciplinary translational research. To facilitate this, we are cluster hiring investigators at all career levels (Assistant, Associate, and Full Professor) into basic science and clinical...

  • Senior Clinical Research Associate

    7 days ago

    Boston, Massachusetts, United States BRIOHEALTH SOLUTIONS INC Full time

    Position Overview: Senior Clinical Research Associate at BrioHealth SolutionsBrioHealth Solutions is on the lookout for skilled Clinical Research Associates (CRAs) to enhance our team and support the development of our cutting-edge LVAS device. As a Senior CRA, you will be instrumental in overseeing clinical trial data and ensuring the effective execution of...

  • News Writer

    1 month ago

    Boston, Massachusetts, United States American Association for Cancer Research Full time

    The American Association for Cancer Research (AACR) has an exciting opportunity for an individual who is passionate about cancer research and excels at scientific communication to join the editorial team of its flagship journal, Cancer Discovery.The News Writer/Reporter, Cancer Discovery, will report to the Senior Editor of Science and Medical News and work...

  • Senior Research Coordinator

    2 months ago

    Boston, Massachusetts, United States Tufts University Full time

    Overview The mission of the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University (HNRCA) is to promote healthy aging through nutrition science to empower people seeking to enjoy long, active, and independent lives. HNRCA investigators conduct the world's most advanced studies on nutrition and aging. The research focuses on determining...

  • News Writer

    5 months ago

    Boston, Massachusetts, United States American Association for Cancer Research Full time

    Cancer Discovery is among the world's most preeminent cancer journals, publishing major advances in basic, translational, and clinical research, including clinical trials.Cancer Discovery is an essential information resource that also publishes highly regarded news stories—including pieces on advances in cancer research and treatment, technology, business,...

  • Research Associate II/Sr. Research Associate I, Protein Crystallography

    4 weeks ago

    Boston, Massachusetts, United States Scorpion Therapeutics Full time

    Scorpion is a pioneering clinical-stage oncology company redefining the frontier of precision medicine to deliver optimized and transformational therapies for larger populations of patients with cancer. Scorpion has built a proprietary and fully integrated platform of the most advanced technologies across cancer biology, medicinal chemistry, and data...

  • Research Support Administrator, College of Arts

    7 days ago

    Boston, Massachusetts, United States InsideHigherEd Full time

    Position Overview:The College of Arts & Sciences at Boston University is seeking a dedicated Research Administration Specialist to join our dynamic team. This role is essential in providing administrative support and technical assistance to faculty, research administrators, and the Associate Deans of the Faculty. The ideal candidate will contribute to...

  • Senior Life Sciences Advisor

    7 days ago

    Boston, Massachusetts, United States Guidehouse Full time

    Job Family:Strategy & Transformation ConsultingTravel Required:Up to 25%Clearance Required:NoneAre you passionate about the life sciences sector? The healthcare landscape is evolving rapidly, with advancements in pharmaceuticals and medical devices paving the way for improved patient outcomes. At Guidehouse, our Life Sciences practice serves as a catalyst...

  • Scientist / Senior Scientist

    2 months ago

    Boston, Massachusetts, United States Elektrofi Full time

    Our breakthrough ultra-high concentration microparticle technology platform resolves the limitations associated with intravenously biologic therapies by enabling convenient at-home subcutaneous self-administration.Elektrofi is looking for a Translational Scientist/ Senior Scientist to support the development of the novel Elektrofi formulation platform.The...

  • Quant Research Associate Intern

    3 weeks ago

    Boston, Massachusetts, United States MFS Investment Management Full time

    At MFS, you will find a culture that supports you in doing what you do best. Our employees work together to reach better outcomes, favoring the strongest idea over the strongest individual. We put people first and demonstrate care and compassion for our community and each other. Because what we do matters – to us as valued professionals and to the millions...

  • Lead Clinical Research Associate

    7 days ago

    Boston, Massachusetts, United States BRIOHEALTH SOLUTIONS INC Full time

    Position Overview: Senior Clinical Research Associate at BrioHealth SolutionsBrioHealth Solutions is in search of committed Clinical Research Associates (CRAs) to enhance our team and support the development of our cutting-edge LVAS device. As a Senior CRA, you will be instrumental in overseeing clinical trial data and ensuring the efficacy of our research...

  • Lead Research Associate in Neurology

    7 days ago

    Boston, Massachusetts, United States Mass General Brigham Full time

    Position Overview: The Yang laboratory, part of the Alzheimer Prevention Program (APP) and Center for Alzheimer Research and Treatment (CART) at Mass General Brigham, is seeking a dedicated and skilled Research Assistant II. Our mission is to enhance the understanding and treatment of Alzheimer's disease and related dementias through a comprehensive and...

  • Advanced Research Associate in Neurology

    6 days ago

    Boston, Massachusetts, United States Mass General Brigham Full time

    Position Overview: The Yang laboratory, part of the Alzheimer Prevention Program (APP) and Center for Alzheimer Research and Treatment (CART) at Mass General Brigham, is seeking a dedicated Research Assistant II. Our mission is to enhance the understanding and treatment of Alzheimer's disease and related conditions through a comprehensive approach that...

  • Lead Research Associate in Neurology

    2 days ago

    Boston, Massachusetts, United States Mass General Brigham Full time

    Position Overview: The Yang laboratory, part of the Alzheimer Prevention Program (APP) and Center for Alzheimer Research and Treatment (CART) at Mass General Brigham, is seeking a dedicated Research Assistant II. Our mission is to enhance the understanding and treatment of Alzheimer's disease and related dementias through a comprehensive, multidisciplinary...

  • Medical Science Liaison

    1 month ago

    Boston, Massachusetts, United States Mallinckrodt Pharmaceuticals Full time

    Job TitleMedical Science Liaison (Ophthalmology)RequisitionJR Medical Science Liaison (Ophthalmology) (Open)LocationARD Field Office - USA405Additional LocationsAtlanta, GA, Boston, MA, Charlotte, NC, Chicago, IL, Columbus, OH, Dallas, TX, Houston, TX, Jackson, MS, Los Angeles, CA, Miami, FL, Minneapolis, MN, Philadelphia, PA, Phoenix, AZJob Description...

  • Clinical Research Associate Manager---Cancer Center Protocol Office

    1 month ago

    Boston, Massachusetts, United States tapwage Full time

    GENERAL SUMMARY/ OVERVIEW STATEMENT:The MGH Cancer Center is seeking a Clinical Research Associate Manager to join their team. The candidate will report directly to the Director of the Gastrointestinal Cancer Center Program and will be responsible for managing a portfolio of projects, including clinical research projects and collaborative research projects...

  • Senior Research Administrator

    1 day ago

    Boston, Massachusetts, United States New England College of Optometry Full time

    Job Summary:The New England College of Optometry is seeking a highly skilled and experienced Senior Research Administrator to provide critical support to our faculty and staff in the development and management of research grants and contracts.Key Responsibilities:Pre-Proposal and Proposal Development Activities:Discuss early phases of project ideas with...