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Sr. Research Associate
2 months ago
Sr. Research Associate
The candidate will work with a multidisciplinary team of scientists and be engaged in the discovery, early development, and testing of novel pharmaceutical products to treat rare diseases.
RESPONSIBILITIES
• Develop, troubleshoot and execute studies of new products in cell-based and other in vitro assays
• Isolate and culture primary cells or cell lines to support in vitro or ex vivo experiments
• Conduct assays to evaluate effects of products on cell responses using a variety of techniques (cellular and molecular biology, immunology, biochemistry, etc)
• Support in vivo studies, including formulation preparation and sample processing and analysis
• Prepare and maintain a constant supply of reagents, buffers and other materials to support in vitro assays
• Collaborate alongside a cross-functional team that includes immunologists, chemists, biologists to drive drug development
• Follow established protocols but also design new protocols
• Perform data and statistical analyses using Excel, GraphPad Prism and FlowJo
• Maintain accurate, detailed and timely records in electronic notebooks and generate internal technical reports as needed
• Summarize experimental results and present findings at internal meetings
• Ensure proper maintenance of laboratory equipment
QUALIFICATIONS
• A Master's degree in the field or biology, immunology or related scientific discipline with 1 year or more work experience, or a B.Sc with equivalent qualification with at least 2 years or more work experience in a related field in an academic and/or industry setting
• Hands-on experience with wide range of cell and molecular biology techniques to characterize in vitro and ex vivo systems that include (but are not limited to) mammalian cell culture, plate-based cell assays, western blotting, qPCR, flow cytometry and ELISA
• Proven experience in optimizing/developing cellular and molecular biology assays e.g. enzymatic or ELISA is required
• Experience working with immune cells and hematopoietic stem cells is a plus
• Experience working with cellular imaging-based instruments and fluorescence microscopy is a plus
• Experience in data processing, analysis, statistics, and data interpretation is required
• Detailed-oriented, meticulous, have sense of urgency, high level of motivation, and research-orientated are required qualities
• High degree of organization and time management is required.
• Strong verbal and written communication skills, as well as a team spirit are required
• Demonstrates an insatiable curiosity, strong work ethic, has the eagerness to rise to challenges and ability to work equally well independently or in a team are key qualities