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Senior Scientist

3 months ago

Cambridge, United States The Fountain Group Full time

Responsibilities:

  • Scientist – in-vitro disease modeling Genome Sciences department is looking for a motivated scientist to lead the identification and validation of new genetic targets for various cardiometabolic diseases including Type 2 Diabetes (T2D), Obesity, Atherosclerosis, Retinal diseases, and vascular diseases. This individual will play a pivotal role as a member of the discovery team, contributing to the development of innovative models for screening drug targets.


Job responsibilities:

  • Establish stem cell-based in-vitro disease platforms.
  • Design assays using high content imaging techniques to facilitate screening of small molecules and genetic modifications using CRISPR.
  • Perform lab experiments, interpret data, and effectively communicate findings.
  • Collaborate with cross-functional teams in therapeutic and functional areas.
  • Maintain electronic lab notebook and sample inventories.


Qualifications:

  • BS with 5+ years of experience/Masters with 3+ years of experience/PHD with 1+ year of experience in a wet lab setting.
  • Candidates with a background in muscle biology will be given preference.


Required experience and skills:

  • Skilled in cell culturing and differentiation of stem cells into specific lineages.
  • Experience with gene manipulation technologies such as CRISPR, siRNA, ASOs, lentivirus, and AAVs.
  • Expertise in molecular biology techniques including RNA extraction, qPCR, ELISA/MSD, and ICC.
  • Critical thinking with an ability to formulate experimental strategies.
  • Effective in working independently and collaboratively within a team.
  • Outstanding verbal and written communication skills.


NOTE:

Position is in Cambridge, MA. This is a lab based onsite role. Candidates must be flexible and able to accommodate the change.