Senior Scientist, Immunology Discovery

4 weeks ago


cambridge, United States Simcere Zaiming Full time

Senior Scientist (Preclinical-Autoimmunity)

Simcere is seeking a Senior Scientist to join our preclinical team to help advance our discovery programs evaluating novel immune regulatory therapies to treat autoimmune and inflammatory diseases. The successful applicant will have a strong background and track record in designing, executing, analyzing, and troubleshooting of experimental approaches required for development of novel therapies for autoimmune diseases. This is an exciting opportunity to be part of a highly collaborative team and to apply your knowledge and experience to develop innovative targets from early discovery to IND-enabling studies using in vitro and in vivo humanized experimental models.

In this position you will be required to:

  • Apply your deep knowledge in immunology, inflammation, and autoimmunity in leading drug discovery programs from target validation to candidate nomination.
  • Design, execute, analyze, and troubleshoot immunological functional assays (multi-color flow cytometry; bioanalytical measurement assays (ELISA, MSD); immune cells interaction, activation, migration, suppression, and proliferation; autoimmune animal models).
  • Collaborate with cross-functional teams to advance the company’s pipeline.
  • Suggest and promote novel therapeutic targets and technologies.
  • Be informed of the scientific advancement in your area of expertise.
  • Interact with different scientists across the company and partners.
  • Provide guidance to junior members of the team.
  • Prepare reports and research documents for publishing, patent, and IND filings.
  • Be able to adapt to changing priorities and deadlines.

Qualifications and experience:

  • A PhD degree in immunology or a related field with at least 5 years of relevant experience.
  • Strong scientific background in understanding pathways involved in autoimmunity and inflammation.
  • Demonstrated experience in execution, analysis, and troubleshooting of immunological assays.
  • Skilled in cellular and molecular immunology techniques.
  • Experience working with mouse autoimmune models.
  • Strong analytical and problem-solving skills.
  • Effective communicator and multitasker with strong record-keeping and organizational skills.
  • Demonstrated a strong scientific record (publications, presentations, and/or patents).
  • Self-motivated, team- and goal-oriented scientist with excellent oral and written communication skills.

What we offer at Simcere:

  • An innovation-driven culture that puts science at the forefront of everything we do.
  • A dynamic, diverse, and inclusive team of experienced scientists applying their skills to some of the most impactful problems in human health.
  • Welcoming and collaborative working environment.
  • Competitive compensation and benefits.



  • Cambridge, United States Simcere Zaiming Full time

    Senior Scientist (Preclinical-Autoimmunity)Simcere is seeking a Senior Scientist to join our preclinical team to help advance our discovery programs evaluating novel immune regulatory therapies to treat autoimmune and inflammatory diseases. The successful applicant will have a strong background and track record in designing, executing, analyzing, and...


  • Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full time

    About the OpportunityCrossbow Therapeutics, Inc. is a biotechnology company dedicated to revolutionizing cancer treatment through innovative immunotherapies. We are seeking a highly skilled Senior Scientist/Principal Scientist, Biology to join our dynamic team.Key Responsibilities:Lead programs from discovery through DC nomination, driving scientific rigor...


  • Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full time

    Crossbow Therapeutics, Inc. is a biotechnology company dedicated to improving the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. Our T-BoltTM therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell targets. Our approach...


  • Cambridge, Massachusetts, United States Montai Therapeutics Full time

    Immunologist Opportunity at Montai TherapeuticsMontai Therapeutics is a pioneering biotechnology company dedicated to transforming healthcare and sustainability through innovative technologies. We are seeking an experienced Immunologist to join our Early Discovery Biology team as a Principal Scientist.About the RoleThis is an exciting opportunity to drive...


  • cambridge, United States Crossbow Therapeutics, Inc Full time

    Crossbow Therapeutics is looking for a Senior Scientist/Principal Scientist, Biology Crossbow Therapeutics, Inc., is a biotechnology company determined to improve the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. The company’s T-Bolt™ therapies are next-generation, easily assembled...


  • Cambridge, United States Crossbow Therapeutics, Inc Full time

    Crossbow Therapeutics is looking for a Senior Scientist/Principal Scientist, Biology Crossbow Therapeutics, Inc., is a biotechnology company determined to improve the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. The company’s T-Bolt™ therapies are next-generation, easily assembled...


  • Cambridge, United States Crossbow Therapeutics, Inc Full time

    Crossbow Therapeutics is looking for a Senior Scientist/Principal Scientist, Biology Crossbow Therapeutics, Inc., is a biotechnology company determined to improve the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. The company’s T-Bolt™ therapies are next-generation, easily assembled...

  • Senior Scientist, II

    3 weeks ago


    Cambridge, Massachusetts, United States AbbVie Full time

    Job OpportunityWe are seeking a highly motivated and talented Senior Scientist II to join our Molecular Profiling and Drug Delivery (MPDD) function within the Small Molecule CMC organization.About the RoleThis role will serve as an MPDD project leader on discovery programs, leading CMC developability assessment for emerging molecules on small molecule...


  • cambridge, United States Third Rock Ventures Full time

    Associate Scientist/Scientist, In vivo pharmacologyA well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking a talented Associate Scientist/Scientist to join the Biology-In vivo pharmacology team. The Associate Scientist/Scientist will serve as the in vivo...


  • Cambridge, United States Third Rock Ventures Full time

    Associate Scientist/Scientist, In vivo pharmacologyA well-funded and highly innovative start up from Third Rock Ventures is emerging out of stealth with a syndicate of marquee investors and is seeking a talented Associate Scientist/Scientist to join the Biology-In vivo pharmacology team. The Associate Scientist/Scientist will serve as the in vivo...


  • Cambridge, Massachusetts, United States Apex Systems Full time

    Job Title: Clinical Research Scientist ImmunologyJob Summary:Apex Systems is seeking a Clinical Research Scientist Immunology to support clinical development through study design, protocol writing, compliance monitoring, and data analysis for regulatory submissions in a dynamic research setting.Key Responsibilities:• Collaborate with a team to support...


  • Cambridge, Massachusetts, United States Synectics Inc Full time

    Job SummaryWe are seeking a highly skilled and motivated scientist to join our Immunology Discovery department in Cambridge, MA. The successful candidate will be responsible for developing therapeutic molecules using recombinant DNA technology, expression, and purification of recombinant proteins, as well as testing purified proteins in functional cellular...

  • Senior Immunologist

    3 weeks ago


    Cambridge, Massachusetts, United States Simcere Zaiming Full time

    Immunology Research ScientistSimcere Zaiming is seeking an Immunology Research Scientist to join our preclinical team and contribute to the advancement of our discovery programs evaluating novel immune regulatory therapies to treat autoimmune and inflammatory diseases.Key Responsibilities:Apply deep knowledge in immunology, inflammation, and autoimmunity to...


  • Cambridge, Massachusetts, United States Flagship Pioneering Full time

    About the Role:We are seeking a highly skilled Senior Research Scientist to join our team at Flagship Pioneering. As a Senior Research Scientist, you will be responsible for developing and applying computational skills to understand complex biological systems and their relationship to clinical state changes.Key Responsibilities:Design and implement novel...


  • Cambridge, Massachusetts, United States Crossbow Therapeutics, Inc Full time

    Crossbow Therapeutics, Inc. is a biotechnology company dedicated to improving the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies.The company's T-BoltTM therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell targets. Our...


  • Cambridge, Massachusetts, United States Kytopen Full time

    Job Title: Senior Scientist, Process DevelopmentKytopen is a pioneering biotech company that is revolutionizing cell engineering for next-generation cell therapies. We are seeking a highly skilled Senior Scientist, Process Development to join our team and contribute to the development of our patent-pending continuous Flowfect non-viral transfection...


  • Cambridge, Massachusetts, United States AbbVie Full time

    AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow.We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan...


  • Cambridge, Massachusetts, United States BioSpace, Inc. Full time

    Immunology Bioinformatics Internship OverviewAt BioSpace, Inc., we are seeking a highly motivated intern to join our Immunology Bioinformatics Team at Genomics Research Center. As a member of our team, you will have the opportunity to work with energetic colleagues and inspirational leaders, gaining world-class experience in one of the most dynamic...

  • Research Scientist

    4 weeks ago


    Cambridge, Massachusetts, United States Orion Group Full time

    Orion Group is seeking a highly motivated and passionate scientist in cellular immunology to join our client's research team in Immunology Discovery based in Cambridge MA.The candidate will focus on making therapeutic molecules using recombinant DNA technology, expression/purification of recombinant proteins, testing purified proteins in functional cellular...


  • Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full time

    Job SummaryWe are seeking a highly motivated and experienced Senior Research Associate to join our Systems Immunology research team. The ideal candidate will have a strong background in immunology and experience in developing and performing immunological assays.The successful candidate will work collaboratively with our team of computational biologists,...