Research Assistant
4 days ago
Job Title: Research Associate
Location: San Diego, CA
Top Skills:
- Expertise in mammalian cell culture
- Experience with plate-based cellular assays
- Immunoblotting, lentiviral infection, cellular transfection, and basic molecular biology techniques experience preferred.
Job Description:
- The Lead Discovery and Optimization Group within Small Molecule Drug Discovery in San Diego focuses on delivering novel therapeutics for disease intervention by engaging E3 ubiquitin ligases for targeted protein degradation. We are seeking a highly driven Research Associate/Senior Research Associate to assist in the identification and characterization of drug candidates for the treatment of human diseases. The successful candidate will work collaboratively in a multi-disciplinary environment to carry out cell-based and molecular assays in support of small molecule discovery for pre-clinical development.
Responsibilities will include but are not limited to the following
- Design and implementation of high-throughput cell-based reporter assays to characterize drug candidates
- Establish stable cell lines via lentiviral transduction and maintain mammalian cell lines
- Conduct routine molecular and cellular experiments including DNA/RNA/protein extraction, immunoblot analysis, and immunoprecipitation
- Assist senior researchers in executing, conducting analyses, and reporting results of experiments
- Familiarity with literature and internal best practices to identify opportunities to improve productivity and quality of work
- Analyze, troubleshoot, and recommend corrective actions for routine problems
- Maintain an accurate, comprehensive, and current laboratory notebook
- Write protocols, procedures and technical reports
- Communicate results via written reports and oral presentations
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