Research Associate, Stem Cell Biology

3 months ago

Cambridge, United States GC Therapeutics Full time

Company Overview


GC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFomeTM was developed in Professor George Church’s lab, a pioneer in synthetic biology, and allows for the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency and speed. GC Therapeutics is based in Cambridge, MA. For additional information, please visit www.gc-tx.com.


Job Purpose


We are seeking a talented and detail-oriented individual to join our growing product optimization group as a research associate. Under the supervision of the team lead and scientists. This candidate will be responsible for the maintenance, differentiation and functional analysis of pluripotent stem cell (PSC) lines and their derivatives to support the development of cell- based therapeutics. The candidate should be coachable, determined, well-organized, responsible, and able to collaborate with other team members.


Duties and Responsibilities


General Laboratory Roles:

  • Participate in the design, planning and execution of experiments.
  • Make observations, analyze results and maintain a detailed laboratory journal.
  • Summarize results and create presentations for internal group meetings.
  • Work with other members of the research team and within GCTx to accomplish company goals.
  • Follow all safe laboratory practices and company policies.


Experimental Techniques:

Cellular Biology

  • Culture PSC lines including maintenance and analysis (e.g. cell culture, transfection, preparation of media, passaging, cryopreservation).
  • Perform cell type differentiation, characterization and experimental endpoint analysis including flow cytometry, ELISA and microscopy.

Molecular Biology

  • Utilize techniques such as PCR, molecular cloning and plasmid isolation.


Qualifications


Essential Qualifications:

  • Experience with mammalian cell culture and preferred experience with PSCs.
  • B.Sc. or M.Sc. degree in biology, cell biology, bioengineering, biochemistry, or related discipline. Preferred prior industry
  • experience.
  • 2+ year track record of lab experience.
  • Proven experience in molecular biology laboratory techniques.
  • Strong project management and organizational skills and ability to prioritize and multitask.
  • Effective communication with excellent organization and interpersonal skills.
  • Ability to work in a laboratory environment approximately 75% of the time including weekend hours.


Additional Preferred Qualifications:

  • Ability to conduct high quality presentations at internal meetings.
  • Authorship on scientific reports and manuscripts.
  • Experience in gene expression analysis and next generation sequencing.
  • Knowledge of R, Python and FlowJo.










Equal Opportunity Workplace: GC Therapeutics is an equal opportunity employer. We provide equal employment opportunities to all applicants for employment and existing employees without regard to ancestry, national origin, place of birth, race, color, gender, sexual orientation, marital status, pregnancy, religion, age, disability, gender identity, results of genetic testing, service in the military or otherwise to the full extent of all federal, state and local laws. GC Therapeutics’ equal employment opportunity policy applies to all terms and conditions of recruiting, hiring, placement, training, compensation, transfer, leave of absence, employment, promotion, layoff and termination of employment.

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