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Associate Scientist/Senior Associate Scientist, Process Chemistry
5 months ago
Asymchem is a leading global integrated Contract Development and Manufacturing Organization (CDMO) providing innovative drug R&D and manufacturing services to the pharmaceutical and biotechnology industries.
Asymchem Boston R&D Center is seeking highly self-motivated candidates for Associate Scientist/Senior Associate Scientist, Process Research and Development of small molecule. This is a laboratory-based position and the Associate Scientist/Senior Associate Scientist is responsible for synthesis, purification, and identification of chemical intermediates and target compounds.
Key Responsibilities:
• Synthesize the known compounds efficiently using literature or in-house procedures, or procedures from the clients’ technical package.
• Synthesize the new compounds by making appropriate modifications of known procedures under supervisory instruction.
• Purify and isolate the target compounds to an appropriate degree using a variety of techniques, which include chromatographic, crystallization/re-slurry, and distillation methods.
• Analyze and help identify the compounds using a range of modern separation and spectroscopic techniques. This will include interpretation of TLC, HPLC, GC, IR, and NMR spectra of moderate complexity.
• Modify the reaction conditions to improve the purity and yields/output under appropriate supervisory direction.
• Develop solutions to routine technical problems of limited scope.
• Contribute to the completion of routine technical tasks.
• Perform scale-up experiments under appropriate supervisory direction.
• Must be able to work in a team environment.
• Manage workload and time effectively to achieve high performance in multiple projects and complete the tasks/experiments outlined by the supervisor.
• Document experiments and data and ensure all necessary paperwork is completed on a timely basis.
• Perform laboratory operations in a safe manner.
• Keep abreast of the Chemical Hygiene Plan.
• Follow responsible actions for chemical disposal.
• Maintain compliance with all regulations at the federal, state, and local levels.
• Contribute and participate in setting up the process chemistry laboratory of Asymchem Boston’s new R&D center.
• Contribute and participate in general laboratory maintenance activities.
• Perform miscellaneous job-related duties as may be reasonably assigned.
Job Qualifications
• Bachelor’s or Master’s Degree with major in chemistry or in a relevant field of science.
• Has a good foundation in general scientific practice and the principles and concepts of a relevant scientific field of study.
• Ability to effectively communicate (oral and written) with supervisor and project team members.
• Motivated, detail-oriented, and quick learner.
• Solid working knowledge of synthetic organic chemistry principles is desirable.
