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Analytical Chemistry Scientist
2 months ago
We are seeking an experienced Analytical Chemistry Scientist to join our team at Ultragenyx. As a key member of our analytical development team, you will play a critical role in developing and qualifying advanced biophysical and analytical methods for AAV vectors.
Key Responsibilities:- Investigate and evaluate cutting-edge biophysical and analytical instrumentation for AAV, AAV-Ab characterization.
- Assess and implement new assay development, such as AUC, SEC or AF4 MALS, HPLCs, CE-SDS, iCIEF, and LC-MS, to determine AAV capsid identity, quality, and quantity.
- Develop methods to quantitatively measure the purity and heterogeneity of AAV gene therapy vectors, including empty capsid, aggregation, and capsid protein purity.
- Provide technical support to cross-function groups and external collaborators.
- Present innovative analytical methods for characterizing and screening AAV products in both internal and external settings.
- Effectively collaborate with internal analytical development teams and manage the transfer of analytical methods to business partners.
- Write, prepare, and present technical data, technical reports, and standard operating procedures (SOPs) for internal use and transfer to external sites.
- Ph.D. in Analytical Chemistry or a related field.
- Proven experience in developing biophysical assays, such as AUC, SEC, or AF4 MALS, HPLCs, CE-SDS, iCIEF, and LC-MS, as it relates to biologics and gene therapy products.
- Strong analytical and problem-solving skills, with the ability to work independently and collaboratively as part of a team.
- Excellent communication and presentation skills, with the ability to effectively communicate complex technical information to both technical and non-technical audiences.
- Ability to stand for extended periods of time with periodic stooping/bending/kneeling.
- Able to lift, push, pull up to 50lbs.
- Climb ladders and stairs of various heights.
- Work in a lab environment requiring special protective clothing over the face, hands, feet, and body.
At Ultragenyx, we are committed to creating a supportive and inclusive environment where our employees can thrive. We offer a range of benefits, including generous vacation time, volunteer days, long-term incentive and employee stock purchase plans, employee wellbeing benefits, fitness reimbursement, tuition sponsoring, and professional development plans.
We are an equal opportunity employer and prohibit unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws.
