Principal Research Scientist I, Genetic Medicine Expert
4 weeks ago
AbbVie is a global biopharmaceutical company committed to developing innovative therapies for serious health conditions. We are seeking a Principal Research Scientist to lead the design and development of fusion proteins for therapeutic purposes suitable for mRNA delivery by nanoparticles.
Key Responsibilities- Characterize expressed protein by biochemical or flow-based techniques and evaluate function by plate-based or cell-based assays.
- Closely collaborate with antibody discovery/production team to bridge between Biotherapeutics and Genetic Medicine.
- Co-lead project with Therapeutic Area to identify and optimize therapeutic candidates and take accountability for project deliverables.
- Analyze experimental data, interpret results, and present findings to internal and external stakeholders.
- Ph.D. in Molecular Biology, Cellular Biology, Biochemistry, or a related field with a minimum of 6 years of relevant industry experience.
- Experience in engineering mAb, dAb, VHH or non-antibody scaffold into multi-domain fusion proteins guided by structural models.
- Up-to-date knowledge in Molecular Biology including translation regulation and hands-on experience with nucleic acid characterization required for mRNA delivery by nanoparticles.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.
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South San Francisco, California, United States Innova Solutions Full timeJob Summary:This is an exciting opportunity to join the Investigative Toxicology Group within the department of Safety Assessment at Innova Solutions. As a Scientist I/II, Investigative Toxicology, you will be responsible for conducting hypothesis-driven research to elucidate the mechanisms underlying toxicities observed non-clinically and/or in clinical...
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Principal Applied Scientist
1 month ago
San Francisco, California, United States Amazon Full timeJob Title: Principal Applied ScientistAmazon is seeking a highly skilled Principal Applied Scientist to join our Responsible AI team. As a key member of this team, you will contribute to the development of new solutions and science best practices in Responsible AI.About the RoleThis is a unique opportunity to work on cutting-edge AI research and development,...
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Biotech Research Scientist
4 weeks ago
South San Francisco, California, United States BioSpace, Inc. Full timeBiotech Research ScientistAt BioSpace, Inc., we're committed to serving patients living with serious illnesses. As a Biotech Research Scientist, you'll play a crucial role in our mission to develop innovative medicines that improve lives.As a member of our team, you'll have the opportunity to explore new research areas and conduct experiments to discover and...
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Principal Machine Learning Scientist
1 month ago
South San Francisco, California, United States Genentech Full timeJob SummaryWe are seeking a highly skilled and motivated Principal Machine Learning Scientist to join the BRAID team within our Computational Sciences organization.This role will focus on building novel machine-learning methods to enhance drug development and clinical trial design, with a particular emphasis on early-stage clinical trials.The successful...
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Biotech Research Scientist
4 weeks ago
South San Francisco, California, United States Amgen Full timeTransforming Lives through Biotech ResearchAt Amgen, we're committed to serving patients living with serious illnesses. As a Biotech Research Scientist, you'll play a crucial role in our mission by exploring new research areas and conducting experiments to discover and validate new targets related to autoimmune and inflammatory diseases.Key Responsibilities:...
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Research Scientist
1 month ago
San Francisco, California, United States TBWA\Chiat\Day Full timeJob Title:Research Scientist - Multimodal AI ExpertJob Summary:We are seeking a highly skilled Research Scientist to join our team at the Chan Zuckerberg Biohub San Francisco. As a Research Scientist, you will design, develop, and implement multimodal large language models that integrate textual, multi-omic, and image data. You will lead the research and...
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Ocular Research Scientist
4 weeks ago
San Diego, California, United States RPM ReSearch Full timeJob DescriptionRPM ReSearch is seeking a highly skilled Ocular Research Scientist to join our team.Key Responsibilities:Assume the functional role of Principal Investigator or Study Director for preclinical ophthalmic studies.Participate in study design and the development and generation of study protocols.Manage the conduct of preclinical studies, evaluate...
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San Francisco, California, United States The University of Texas MD Anderson Cancer Center Full timeJob Title: Principal Scientist/Director, Chemical BiologyJob DescriptionAt General Proximity, we are seeking a highly skilled chemical biologist to join our Platform/Drug Discovery Team. As a key member of our team, you will play a crucial role in the development of our core drug discovery technology and the generation of a novel class of therapeutics.About...
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Biotech Research Scientist
4 weeks ago
South San Francisco, California, United States BioSpace, Inc. Full timeUnlock the Power of Biotech ResearchAt BioSpace, Inc., we're committed to pioneering the world of biotech in our fight against the world's toughest diseases. As a member of our team, you'll have the opportunity to make a lasting impact on the lives of patients by researching, manufacturing, and delivering innovative medicines to help people live longer,...
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Principal Applied Scientist
4 days ago
San Diego, California, United States Amazon Services LLC - A57 Full timeAbout the JobWe are seeking a highly skilled Principal Applied Scientist to join our Amazon Private Brands Selection Guidance organization in building science and tech solutions at scale to delight our customers with products across our leading private brands.The Selection Guidance team applies Generative AI, Machine Learning, Statistics, and Economics...
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Research Scientist
1 month ago
San Francisco, California, United States University of California , San Francisco Full timeAbout the PositionWe are seeking a highly motivated and experienced Research Scientist to join our team at the University of California, San Francisco. The successful candidate will have a strong background in both computational biology and molecular biology, with expertise in single-cell and spatial genomics, machine learning, statistics, and molecular...
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Senior Research Scientist, Veterinary Expert
4 weeks ago
San Diego, California, United States Pharmaron Beijing Co. Ltd. Full timeRole Overview:The Principal Scientist within our Medical Device team is a pivotal role requiring a dynamic professional with strong experience in serving as a Study Director and expertise in surgical studies.You will be supporting business development activities, overseeing study execution, preparing study reports, and data analysis while serving as the...
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Principal Scientist, Discovery Immunology
1 month ago
South San Francisco, California, United States Parvus Therapeutics Full timeJob Title: Principal Scientist, Discovery ImmunologyParvus Therapeutics Inc. is a biopharmaceutical company developing innovative treatments for autoimmune diseases. We are seeking a Principal Scientist to join our Discovery Immunology Team and contribute to the development of our Navacims platform.Key Responsibilities:Lead the identification and selection...
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Veterinary Research Scientist
4 weeks ago
San Diego, California, United States RPM ReSearch Full timeJob OverviewRPM ReSearch is seeking a highly skilled Veterinary Research Scientist to join our team. The successful candidate will be responsible for developing and supporting in vivo models to screen therapeutics and devices being developed for various disorders.Key Responsibilities:Perform surgical support and provide technical expertise to facilitate...
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Research Scientist
1 month ago
San Francisco, California, United States University of California , San Francisco Full timeJob Title:Research Scientist - Computational BiologyJob Summary:We are seeking a highly motivated Research Scientist to join our team at the University of California, San Francisco. The successful candidate will have a strong background in computational biology and molecular biology, with expertise in single-cell and spatial genomics, machine learning,...
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Senior Research Scientist
4 weeks ago
South San Francisco, California, United States Genentech Full timeKey Responsibilities:As a member of our dynamic team at Genentech, you will be responsible for:Discovering and evaluating candidate targets or biomarkers to drive innovation in translational medicine.Developing and implementing biomarker assays in preclinical models and clinical trials to advance our understanding of respiratory diseases.Evaluating new...
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Principal Scientist Pharmacometrics Lead
4 weeks ago
San Diego, California, United States Affinity Executive Search Full timeJob Title: Principal Scientist PharmacometricsA top-tier BioPharmaceutical company is seeking a highly skilled Principal Scientist to join their dynamic Pharmacometrics team.The Pharmacometrics Group applies a range of model-informed drug development (MIDD) approaches to support early and late-stage development of small and large molecules.We are looking for...
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San Francisco, California, United States Genentech Full timeJob SummaryWe are seeking a highly motivated Principal Scientist to drive our biomarker discovery and drug development efforts in immunology and respiratory diseases. The successful candidate will have a strong background in translational research, with expertise in preclinical and clinical sample collection/processing and molecular/immunological...
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Clinical Research Scientist
4 weeks ago
South San Francisco, California, United States Lifelancer Full timeJob Title: Clinical ScientistJob Description:We are seeking a Clinical Scientist to contribute to the design, conduct, analysis, and reporting of clinical trials. The ideal candidate will have a strong background in scientific training and clinical research experience.Responsibilities:Contribute to the review, interpretation, and communication of scientific...
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Senior Principal Scientist
4 weeks ago
San Diego, California, United States Pfizer Full timePfizer's Oncology Research Unit (ORU) in La Jolla, California, is seeking a Senior Principal Scientist (PhD) to join the Tumor Immunity team focused on delivering breakthroughs that change patients' lives by redirecting the immune system against cancer.The Senior Principal Scientist will be responsible for driving scientific strategies and their...