Senior Research Scientist

2 months ago

Seattle, United States University of Washington Department of Laboratory Medicine & Pathology Full time

The Senior Research Scientist will collaborate with Dr. Alex Greninger to conceive and develop projects and plans for clinical immune profiling of viral diseases, including developing and validating bespoke high-throughput binding serologies, functional serologies such as neutralization/pseudoneutralization assays, TCR/BCR sequencing, cellular immunity assays, cytokine assays, and Fc characterization assays, and subsequent performance of assays and/or direction of technical personnel.

WHAT WE OFFER

Vacation time and sick time off that accrues monthly, including 12 paid holidays. Excellent healthcare, dental, disability, and retirement plan options. Fully subsidized public transit pass (U-PASS) that covers multiple forms of public transportation in the region. Eligibility for the Public Service Loan Forgiveness Program as a full-time UW employee. State Employee Tuition Exemption Program covering up to 6 credits of qualifying coursework per quarter at the University of Washington or other participating colleges or universities. Lots of free fitness, health eating, finance, and stress reduction classes offered through the Whole U.

WHAT YOU'LL DO

Research/Project Management (80%):

Responsible for the technical and development of the research projects and experiments in Virology, to support research in optimizing of high-complexity immunological assays, and process improvement that will be used for the Virology Division. This will include coordinating research efforts in laboratory automation of serological and cellular immunity assays across the division. Lead automation efforts in the Virology research laboratories involving liquid handlers. Develop process improvements in workflow of high complexity immunology tests. Develop and implement clinical research validation to be used for virologic test services based on binding and functional serologies and cellular immunity assays Facilitate and lead the research process of streamlining and harmonization of wet bench aspects of immunology workflows across Virology Division laboratories. Plans, develops, and coordinates research and development of technical workflows and facilities of Virology Division laboratories. Oversee the creation of technical development documentation (validation document, procedures) for new and updated Virology Division tests from research to specification required by regulatory agencies, including CAP, CLIA, FDA, Study Sponsors, and PIs. Negotiate with vendors for reagents and instrumentation needed for expanded immunology services across the Virology Division laboratories. Review current Virology Division technical development plans and assist in planning for annual division research and development technical goals and objectives. Interact with laboratory clients (physician and other medical providers) related to aspects of technical development. Assist in test interpretation and test reporting from research validated tests. Review high-complexity quality control data for Virology Division laboratories. Participate, as needed, in teaching of undergraduates, graduate students, residents, and fellows. Participate in research and scholarship related to the Virology Division leadership. Other duties as assigned.

Supervisory/Managerial (20%):

Directly supervise the employees assigned to work in the Greninger Laboratory, including hiring, training, daily oversight, mentoring, scheduling and prioritization of tasks evaluation of performance, development and implementation of performance improvement plans and corrective action, and management of leave requests

WHAT YOU'LL NEED

Minimum Requirements:

PhD in Immunology, Virology, Biology, Molecular Biology, Microbiology or closely related field AND six (6) years in collaborative project design within clinical immunology and/or viral biology OR the equivalent combination of education/experience. Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.

Additional Requirements:

Expertise in primer/probe design for PCR Genomic assay design and different genomic library preparation and analysis techniques Strong collaborative skills Experience in evaluation of viral sequence diversity Evidence of strong writing skills and ability to bring projects to completion

Desired Qualifications: 

Good communication and writing skills Ability to analyze PCR data

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